Topoisomerase expression in oral squamous cell carcinoma: relationship with cancer stem cells profiles and lymph node metastasis
Journal of Oral Pathology & Medicine, 06/12/2012
Oliveira–Costa JP et al. – The results that all topoisomerases correlates with oral squamous cell carcinoma (OSCC) cancer stem cells (CSCs) may indicate a role for topoisomerases in head and neck carcinogenesis. Notwithstanding, it is plausible that other members of topoisomerases family could represent novel therapeutical targets in oral squamous cell carcinoma.



