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See Latest ArticlesDevelopment of a gene transfer-based treatment for radiation-induced salivary hypofunction
Oral Oncology , 11/09/09
Baum BJ et al. – This brief review describes the efforts to develop a gene transfer approach, employing the aquaporin–1 cDNA, to treat patients with existing radiation–induced salivary hypofunction. A Phase I/II clinical trial, using a recombinant adenoviral vector to mediate gene transfer, is currently underway.
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