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Association of functional gene polymorphism IL-1beta in patients with external apical root resorption
American Journal of Orthodontics and Dentofacial Orthopedics, 10/30/09
Lages EMB et al. – External apical root resorption (EARR) is a frequent complication of orthodontic treatment. Interleukin 1beta (IL–1beta) is a potent stimulus for bone resorption and osteoclastic cell recruitment during orthodontic tooth movement. The purpose of this study was to assess the association between a polymorphism in the IL–1beta genes and EARR during orthodontic treatment. The polymorphism of the IL–1beta gene is associated with root resorption in the studied population.
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