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Immortalization of ameloblastoma cells via reactivation of telomerase function: Phenotypic and molecular characteristics
Oral Oncology , 10/23/09
Tao Q et al. – Ameloblastoma (AM) is recognized as a benign tumour but locally invasive with a high risk of recurrence. In vitro model systems for studying AM are limited due to the fact that AM cells grow poorly and begin to senesce early. The hTERT–immortalized cell line may be a potentially valuable and reliable cell model for further study of the invasive properties of AM in vitro.
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