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The Impact of Fluoride on Ameloblasts and the Mechanisms of Enamel Fluorosis
Journal of Dental Research , 10/12/09
Bronckers ALJJ et al. – Fluoride can directly affect the ameloblasts, particularly at high fluoride levels, while at lower fluoride levels, the ameloblasts may respond to local effects of fluoride on the mineralizing matrix. A new working model is presented, focused on the assumption that fluoride increases the rate of mineral formation, resulting in a greater release of protons into the forming enamel matrix.
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