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Changes in cell characteristics due to retinoic acid; specifically, a decrease in the expression of claudin-1 and increase in claudin-4 within tight junctions in stratified oral keratinocytes
Journal of Periodontal Research, 10/08/09
Hatakeyama S et al. – Retinoic acid changed the expression of tight junction constituent molecules, such as claudin–1 and claudin–4, in oral keratinocytes. These findings suggest that long–term application of retinoids in clinical therapy should be carefully performed.
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