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Paranaiba LMR et al. – Interferon regulatory factor 6 (IRF6) gene has emerged as a potential susceptibility gene for non–syndromic cleft lip and/or palate (NSCL/P) in different populations. The findings are consistent with a lack of involvement of IRF6 rs2235371 and rs642961 polymorphisms in the NSCL/P pathogenesis in the Brazilian population.


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