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Novel RUNX2 Mutations in Chinese Individuals with Cleidocranial Dysplasia
Journal of Dental Research , 09/25/09
Zhang CY et al. – Cleidocranial dysplasia (CCD) is an inherited autosomal–dominant skeletal disease caused by heterozygous mutations in the osteoblast–specific transcription factor, RUNX2. The results provide new genetic evidence that mutations involved in RUNX2 contribute to CCD.
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