Dentistry Medical News about Purine Degradation

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Acceleration of Purine Degradation by Periodontal Diseases
Journal of Dental Research , 09/28/09

Barnes VM et al. – Periodontal diseases, such as gingivitis and periodontitis, are characterized by bacterial plaque accumulation around the gingival crevice and the subsequent inflammation and destruction of host tissues. The findings provide new mechanistic insights and a panel of comprehensive biomarkers for periodontal disease progression.

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Central Insulin Signaling Is Attenuated by Long-Term Insulin Exposure via Insulin Receptor Substrate-1 Serine Phosphorylation, Proteasomal Degradation, and Lysosomal Insulin Receptor Degradation
Endocrinology, 11/06/09 Relevance Score: 45%

SKP2 and CKS1 Promote Degradation of Cell Cycle Regulators and Are Associated With Hepatocellular Carcinoma Prognosis
Gastroenterology, 10/29/09 Relevance Score: 43%

Therapy-induced PML/RARA Proteolysis and Acute Promyelocytic Leukemia Cure
Clinical Cancer Research, 10/12/09 Relevance Score: 43%

Which elements are involved in reversible and irreversible cartilage degradation in osteoarthritis
Rheumatology International, 10/15/09 Relevance Score: 42%

Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin–proteasome pathway
Oncogene, 10/08/09 Relevance Score: 42%