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Entry of Porphyromonas gingivalis outer membrane vesicles into epithelial cells causes cellular functional impairment
Infection and Immunity, 09/29/09

Furuta N et al. – The findings suggest that following entry of P. gingivalis MVs into host cells, MV–associated gingipains degrade cellular functional molecules such as TfR and paxillin/FAK, resulting in cellular impairment, indicating that P. gingivalis MVs are potent vehicles for transmission of virulence factors into host cells and involved in the etiology of periodontitis.

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