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Cionca N et al. – It has been suggested that prescription of systemic antibiotics should be limited to patients with specific microbiological profiles. The main purpose of the present analysis was to study whether microbiological testing before therapy was of value in predicting which patients would specifically benefit from adjunctive amoxicillin and metronidazole, given in the context of full–mouth scaling and root planing (SRP) within 48 hours. Excellent clinical results in the antibiotics group were obtained irrespective of the presence or absence of 6 classical periodontal periopathogens prior to treatment.

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