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Effects of Periodontal Therapy on Rate of Preterm Delivery: A Randomized Controlled Trial
Obstetrics and Gynecology, 08/25/09

Offenbacher S et al. – Periodontal therapy did not reduce the incidence of preterm delivery.

• A randomized, treatment–masked, controlled clinical trial.
• Participants were assigned to either a periodontal treatment arm, consisting of scaling and root planing early in the second trimester, or a delayed treatment arm that provided periodontal care after delivery.
• Pregnancy and maternal periodontal status were followed to delivery and neonatal outcomes until discharge.
• The primary outcome (gestational age less than 37 weeks) and the secondary outcome (gestational age less than 35 weeks) were analyzed using a ?2 test of equality of two proportions.

• At baseline, there were no differences comparing the treatment and control arms for any of the periodontal or obstetric measures.
• The rate of preterm delivery for the treatment group was 13.1% and 11.5% for the control group.
• There were no significant differences when comparing women in the treatment group with those in the control group with regard to the adverse event rate or the major obstetric and neonatal outcomes.

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