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Intranasal flumazenil and naloxone to reverse over-sedation in a child undergoing dental restorations
Paediatric Anaesthesia, 07/31/09

Heard C et al. – The authors describe a 3–year–old child who became over–sedated after receiving intranasal (IN) midazolam (0.53 mg·kg-1) and IN sufentanil (1 mcg·kg-1) for dental restorations in the dental office. Desaturation was attributed to laryngospasm, which was managed with positive pressure ventilation and oxygen. The sedation was reversed with a combination of IN flumazenil and naloxone.

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