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Oxidant–antioxidant status in blood and tumor tissue of oral squamous cell carcinoma patients
Oral Diseases , 07/31/09

Gokul S et al. – Increased levels of MDA and NO indicate an increase in the oxidative stress in OSCC patients associated with a deficient antioxidant defense mechanism. This oxidant–antioxidant imbalance may be considered as one of the factors responsible for pathogenesis of cancer.

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S Gokul, 08/03/09

Oxidative stress in the form of excessive reactive oxygen species or inadequate antioxidant defense plays an important role in the initiation and progression of head and neck cancer. Estimation of these values may serve as a marker in the post operative follow up of surgically treated cases and may aid in selecting radiotherapy or chemotherapy. Estimation of these values in pre-cancerous conditions may be useful in early diagnosis of head and neck malignancies.

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