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Acetylcholinesterase inhibitor is a potentially useful therapeutic agent for nicotine-induced periodontal disease
Medical Hypotheses, 07/28/09
Wang Y et al. – The authors hypothesize that there is a non–neuronal cholinergic system in periodontal tissue that is activated by excess nicotine, which increases expression of AChE, thus increasing apoptosis of periodontal cells. If so, the introduction of an AChE inhibitor should decrease periodontal cell apoptosis, lessening periodontal disease.
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