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See Latest ArticlesOsteoprotegerin induces osteopontin via syndecan-1 and phosphoinositol 3-kinase/Akt in human periodontal ligament cells
Journal of Periodontal Research, 07/16/09
Yongchaitrakul T et al. - An increased level of osteoprotegerin can generate signals via a RANKL/syndecan-1/phosphoinositol 3-kinase/Akt pathway. The results also suggest that osteopontin is one of the downstream targets of the pathway mediated by osteoprotegerin in human periodontal ligament cells. Thus, in addition to counteracting RANKL in the RANKL–osteoprotegerin system, osteoprotegerin may play a role in periodontal tissue remodeling through modulation of the extracellular matrix.
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Today in Basic Science...keeping you current
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KO-202125, a sauristolactam derivate, induces apoptosis to prevent KB human oral squamous carcinoma cells through inhibition of cyclooxygenase-2 expression
European Journal of Cancer Prevention, 12/08/09
De novo mutation in the DSPP gene associated with dentinogenesis imperfecta type II in a Japanese family
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Today in Periodontics...keeping you current
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An Exploration of Shared Genetic Risk Factors Between Periodontal Disease and Cancers: A Prospective Co-Twin Study
American Journal of Epidemiology, 12/08/09
Influence of Diet and Salivary Characteristics on the Prevalence of Dental Erosion among 12-year-old Schoolchildren
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