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PTHrP Induces Notch Signaling in Periodontal Ligament Cells
Journal of Dental Research , 07/23/09
Nakao A et al. – Periodontal ligament (PDL) cells are known to play important roles in tooth eruption and alveolar bone metabolism. PTHrP induces Jagged1 expression in PDL cells, leading to osteo– and odontoclastogenesis, and thus likely promoting tooth and alveolar bone resorption.
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