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Niu Y et al. - Mutans streptococci (MS) are generally considered to be the principal etiological agent of dental caries. The authors cloned the catalytic (cat) fragment of S. sobrinus gtf-I, which demonstrated its ability to inhibit water-insoluble glucan synthesis by S. sobrinus, into pGJA-P/VAX to produce a new anti-caries DNA vaccine.

 

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