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Ashraf H et al. - The results showed that cytotoxicity of GF was less than GP when assessed at 24 h and 72 h, but there was no significant difference at 1 h. In GF, the most and least cytotoxicity were observed at 24 h and 72 h while cytotoxicity of GP increased with time.

Exclusive Author Commentary
Hengameh Ashraf, 06/01/09

Our research has shown less cytotoxicity of Guttaflow in short time. It is important to show biological compatibility in regard to bone formation in long term.In order to practice with other techniques,such as intraosseous implantation in rats is suggested.

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