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The Anesthetic Efficacy of Diphenhydramine and the Combination Diphenhydramine/Lidocaine for the Inferior Alveolar Nerve Block
Journal of Endodontics, 11/26/08
Willett J et al. - They concluded that a 1% diphenhydramine solution should be used cautiously for the inferior alveolar nerve block. The combination lidocaine/diphenhydramine solution was irritating postinjection and was not as effective as a lidocaine solution for pulpal anesthesia.
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