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Wogelius P et al. - In 647 children with four fully erupted permanent 1st molars, the prevalence of demarcated opacities and of lesions with loss of tooth substance due to demarcated opacities in any 1st molar was 37.3% and 6.3%, respectively. Permanent incisors were 2.5 times more frequently affected among children with one or more affected permanent 1st molar than among children with no such teeth. Demarcated creamy-white opacities were the type of lesion found most frequently, and the most frequently affected tooth types were the upper central incisors followed by 1st molars.

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