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Ciclosporin A-induced gingival enlargement. Clinical and microbiological modifications after conversion to the medication tacrolimus
Periodontal Practice Today, 09/15/08
Purschwitz R et al. - Significant improvements were found in the probing depth, the hyperplasia index and the papillary gingival width after 8 and 26 weeks as well as in the marginal gingival width after 8 weeks. T. forsythia was significantly reduced at the end of the study into subgingival plaque. The change in medication from ciclosporin A to tacrolimus had positive effects on clinical variables and the subgingival biofilm.
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