Safety and efficacy of a high-adhesion whitening strip under extended wear regimen

Journal of Dentistry, 02/13/2013

This randomized, parallel group, single centre clinical trial was conducted to evaluate the safety and compare the whitening efficacy for an extended wear of an experimental 9.5% H2O2 high–adhesion whitening strip, relative to a marketed 10% H2O2 control strip. The 2–h regimen for the 9.5% H2O2 high–adhesion whitening strip was more efficient for tooth whitening than the 30–min regimen of 10% H2O2 whitening strip. Both treatments were well tolerated and the use of the test products during the study time frame was considered safe. Extending the daily wear time of whitening strips can improve the efficacy of the treatment and ultimately shorten the length of the treatment without any significant adverse effects.

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