Efficacy of Chlorhexidine Varnish for the Prevention of Adult Caries: A Randomized Trial

Journal of Dental Research , 01/24/2012

The authors observed no significant difference between the two treatment arms in either the intention–to–treat or per–protocol analyses. Analysis of 3 protocol–specified secondary outcomes produced similar findings. This trial failed to find that 10% (w/v) chlorhexidine diacetate coating was superior to placebo coating for the prevention of new caries.

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