Comparison of ropivacaine and articaine with epinephrine for infiltration anaesthesia in dentistry – a randomized study

International Endodontic Journal, 04/15/2011

Ropivacaine (0.5%) achieved effective and long duration of uninflamed pulp and soft tissue anaesthesia. The mean onset time was significantly shorter for ropivacaine (2.22 min) when compared with articaine (4.08 min). The duration of action and soft tissue anaesthesia were also significantly longer for ropivacaine (79.2 and 264 min) when compared with articaine (63.7 and 195.2 min, respectively). Ropivacaine caused significant increases in blood pressure and heart rate.

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