In Vitro Cytotoxicity Evaluation of a Self-adhesive, Methacrylate Resin–based Root Canal Sealer Pinna L et al. - All sealers exhibited severe toxicity at 72 hours, after which toxicity decreased gradually over the experimental period except for Pulp Canal Sealer, which remained severely toxic. MetaSEAL was more toxic than AH Plus Jet during the first week. Both were similar to the toxicity profile of the positive control after the first week, which was probably diffusion controlled. [more...]