A Retrospective Comparative Study of 2-Drug Oral and Intramuscular Cephalosporin Treatment Regimens for Pharyngeal Gonorrhea
Clinical Infectious Diseases, May 9, 2013
Barbee LA et al. - The Centers for Disease Control and Prevention guidelines for pharyngeal gonorrhea treatment recommend dual therapy with intramuscular ceftriaxone and either azithromycin or doxycycline. Few clinical data exist to support this recommendation. In this retrospective study, dual therapy with an oral third-generation cephalosporin and azithromycin was comparable to ceftriaxone-based regimens in the treatment of pharyngeal gonorrhea. Combination oral therapy ...
Adolescent pharyngitis: a common complaint with potentially lethal complications
The Journal for Nurse Practitioners , May 16, 2013
Nicoteri JAL - Acute pharyngitis is 1 of the 20 most common primary care diagnoses in the United States. The majority are attributed to viral etiologies or allergic rhinitis. Although Group A β-hemolytic streptococcus (GABHS) or Streptococcus pyogenes are the main bacterial causes of pharyngitis, new bacteria, specifically Fusobacterium necrophorum, are emerging. Rare yet potentially fatal complications—peritonsillar abscess or Lemierre’s Syndrome—may also occur. The latest ...
Effect of clinical spectrum, inoculum size and physician characteristics on sensitivity of a rapid antigen detection test for group A streptococcal pharyngitis
European Journal of Clinical Microbiology & Infectious Diseases, May 20, 2013
Cohen JF et al. - The authors aimed to assess the independent effect of clinical spectrum, bacterial inoculum size and physician characteristics on the sensitivity of a rapid antigen detection test (RADT) for group A streptococcus (GAS) in children. Physicians who base their diagnosis of GAS pharyngitis on the results of a RADT alone should consider diagnostic accuracy monitoring and adequate training when needed.
Accuracy and interobserver variation of three clinical decision rules for the diagnosis of streptococcal pharyngitis
The Pediatric Infectious Disease Journal, May 23, 2013
Orofino DHG et al. - The authors evaluated the accuracy and interobserver variation of 3 clinical decision rules for streptoccocal pharyngitis diagnosis. Oropharyngeal swab culture was the reference. The Abu Reesh rule had the highest sensitivity and the World Health Organization rule showed the highest specificity. The interobserver variation of those rules indicates the need for better training of clinicians.
A minimally invasive method to prevent postlaryngectomy major pharyngocutaneous fistula using infrahyoid myofascial flap
Journal of Plastic, Reconstructive & Aesthetic Surgery, May 2, 2013
Kadota H et al. - The study aims to prevent postoperative pharyngocutaneous fistula (PCF) after total (pharyngo)laryngectomy, simultaneous coverage of pharyngeal anastomosis with vascularised flaps such as pectoralis major muscle, anterolateral thigh or radial forearm, has been reported to be effective. As an alternative to the invasive methods using distant flaps, the authors used the infrahyoid myofascial flap (IHMFF), which was harvested from the same operation field of ...
Oropharyngeal Dysphagia and Gross Motor Skills in Children With Cerebral Palsy
Pediatrics, May 6, 2013
Benfer KA et al. – To determine the prevalence of oropharyngeal dysphagia (OPD) and its subtypes (oral phase, pharyngeal phase, saliva control), and their relationship to gross motor functional skills in preschool children with cerebral palsy (CP). It was hypothesized that OPD would be present across all gross motor severity levels, and children with more severe gross motor function would have increased prevalence and severity of OPD. OPD was present across all levels of gross motor severity ...
Different antibiotic treatments for group A streptococcal pharyngitis
Cochrane Reviews, May 9, 2013
Van Driel ML et al. - Antibiotics provide only modest benefit in treating sore throat, although effectiveness increases in participants with positive throat swabs for group A beta-haemolytic streptococci (GABHS). It is unclear which antibiotic is the best choice if antibiotics are indicated. Evidence is insufficient to show clinically meaningful differences between antibiotics for GABHS tonsillopharyngitis. Limited evidence in adults suggests cephalosporins are more effective than ...
Trans-oral resection of large parapharyngeal space tumours
European Archives of Oto-Rhino-Laryngology, May 14, 2013
Hussain A et al. - The aim of this study is to describe minimally invasive trans-oral approach for resection of parapharyngeal space (PPS) tumours and to demonstrate surgical technique, resection, repair and outcomes. The authors have demonstrated successful and safe execution of trans-oral resection of large PPS tumours. There were no intra and post-operative complications and there has been no recurrence during the follow-up period. In the experience, it appears ...
Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study
Intensive Care Medicine, March 15, 2013
Milesi C et al. – The high flow nasal cannula (HFNC) has recently been proposed to support infants with respiratory syncytial virus (RSV)–related respiratory distress. The authors assessed the capacity of HFNC to generate positive airway pressure, as well as the resulting effects on breathing pattern and respiratory effort. HFNC with a flow rate equal to or above 2L/kg/min generated a clinically relevant PP, with improved breathing pattern and rapid unloading of respiratory muscles, in young ...
Effects of mandibular advancement surgery combined with minimal maxillary displacement on the volume and most restricted cross-sectional area of the pharyngeal airway
International Journal of Oral and Maxillofacial Surgery, May 23, 2013
Valladares-Neto J et al. - The purpose of this study was to evaluate changes in the volume and most restricted cross-sectional area of the pharyngeal airway as a result of mandibular advancement surgery with minimal maxillary displacement, and to ascertain the change in height of this restricted area and whether gender and age could influence these results. Using binomial and multiple logistic regression tests, this constricted site presented an unpredictable change in ...