Single nucleotide polymorphisms of complement component 5 and periodontitis
Journal of Periodontal Research, 11/11/2009
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Chai L et al. – Polymorphisms of host defence genes might increase one's risks for periodontitis. This study investigated whether tagging single nucleotide polymorphisms (SNPs) of the gene encoding complement component 5 (C5) are associated with periodontitis in a Hong ... Chinese population. The tagging SNP rs17611 of the C5 gene and smoking may be associated with periodontitis among the Hong Kong Chinese population.
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Clinical Effect of Subgingivally Delivered Simvastatin in the Treatment of Chronic Periodontitis Patients: A Randomized Clinical Trial
Journal of Periodontology, 10/06/2009
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Pradeep AR et al. – Within the limits of this study, there was greater reduction in gingival index and PPD, and more RAL gain with significant IBD fill at sites treated with SRP plus locally delivered SMV in chronic periodontitis patients ... periodontics,clinical pharmacology
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Association of Gingival Crevicular Fluid Biomarkers During Periodontal Maintenance With Subsequent Progressive Periodontitis
Journal of Periodontology, 11/06/2009
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Reinhardt RA et al. – These data support the hypothesis that elevated GCF biomarkers of inflammation and bone resorption from a small number of moderate/deep sites hold promise in identifying patients vulnerable to progressive periodontitis, and SDD may modify that ... periodontics
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Confounding and interaction effect of Treponema denticola salivary carriage in chronic periodontitis
Oral Diseases, 10/23/2009
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Martinez–Pabon MC et al. – Although salivary carriage of T. denticola may be a risk indicator for CP, its pathogenicity should not be exclusively endorsed to its detection in saliva ... with some demographic characteristics of the susceptible host.
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Characterization of bacterial flora in persistent apical periodontitis lesions
Oral Microbiology and Immunology, 10/15/2009
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Fujii R et al. – The microbiota of persistent apical periodontitis lesions is composed by diverse types of microorganisms with biofilm–forming capacity, including P. acnes, S. epidermidis and F. nucleatum.
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Progression of chronic periodontitis can be predicted by the levels of Porphyromonas gingivalis and Treponema denticola in subgingival plaque
Oral Microbiology and Immunology, 10/14/2009
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Byrne SJ et al. – Monitoring the proportions of P. gingivalis and T. denticola in subgingival plaque has the potential to help identify sites at ... progression of periodontitis, which would assist in the targeted treatment of disease.
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Salivary interleukin-1beta concentration and the presence of multiple pathogens in periodontitis
Journal of Clinical Periodontology, 10/09/2009
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Gursoy UK et al. – The authors suggest that salivary IL–1beta and the presence of multiple periodontal pathogens in saliva should be studied more thoroughly as markers of periodontitis.
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Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease
Atherosclerosis, 10/08/2009
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Higashi Y et al. – The findings suggest that periodontitis is associated with endothelial dysfunction in patients with CAD through a decrease in nitric ... inflammation may be, at least in part, a cause and predictor of progression of endothelial dysfunction.
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Increased levels of circulating endothelial progenitor cells in subjects with moderate to severe chronic periodontitis
Journal of Clinical Periodontology, 10/08/2009
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Li X et al. – Emerging evidence shows that periodontal disease is associated with endothelial dysfunction. The purpose of this study was to determine the association between chronic periodontitis (CP) and circulating endothelial ... first time that moderate to severe CP is associated with an increased level of circulating EPC.
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Antimicrobial susceptibility of moxifloxacin against Gram-negative enteric rods from Colombian chronic periodontitis patients
Journal of Periodontology, 11/02/2009
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Ardila CM et al. – This study found high levels of Gram–negative enteric rods in chronic periodontitis patients. Moxifloxacin and ciprofloxacin appear to be capable of eradicating these ... negative enteric rods and periodontopathogens suggests the potential use of moxifloxacin as an adjunctive antibiotic in the treatment of mixed periodontal infections.
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