Aggressive periodontitis in children: a 14–19-year follow-up
Journal of Clinical Periodontology, 01/20/2010
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Mros ST et al. – The objective was to assess the recurrence of disease in subjects with a history of localized aggressive periodontitis (LAP). Children treated for LAP do not always exhibit recurrence of periodontitis in the ... supportive periodontal therapy over periods of 14–19 years.
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Association of ALDH2 Genotypes with Periodontitis Progression
Journal of Dental Research, 01/22/2010
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Nishida N et al. – The authors examined the prospective association of ALDH2 genotypes in terms of alcohol sensitivity between alcohol consumption and periodontal disease progression. The results suggested that alcohol consumption ... be a risk factor for periodontitis progression.
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Alteration of PTGS2 Promoter Methylation in Chronic Periodontitis
Journal of Dental Research, 01/25/2010
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Zhang S et al. – In chronically inflamed tissues, there is a hypermethylation pattern of the PTGS2 promoter in association with a lower level of PTGS2 transcription, consistent with a dampening of COX–2 expression in chronic periodontitis. These findings ... chronic persistence of the biofilm and inflammation may be associated with epigenetic changes in local tissues at the biofilm–gingival interface.
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Validation of an Algorithm for Chronic Periodontitis Risk Assessment and Prognostication. Risk Predictors, Explanatory Values, Measures of Quality and Clinical Utility
Journal of Periodontology, 02/02/2010
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Lindskog S et al. – The predictors included in the algorithm reflect a relevant selection for periodontitis risk assessment. Risk ... with the algorithm provides the clinician with a validated, reliable, consistent and objective tool supporting treatment planning.
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Salivary soluble CD44 levels in smoker and non-smoker subjects with chronic periodontitis: A pilot study
Journal of Periodontology, 01/20/2010
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Ghallab N et al. – Salivary sCD44 might be considered as a biomarker of periodontal destruction in smokers as well as non–smokers. The research opens the door to further research into a role for CD44 as a diagnostic marker for periodontitis ... chronic periodontitis periodontitis
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Genetic variants associated with neutrophil function in aggressive periodontitis and healthy controls
Journal of Periodontology, 02/01/2010
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Nibali L et al. – This study confirms previous reports of a higher oxidative burst associated with AgP and brings preliminary evidence that genetic factors may influence neutrophil function ... aggressive periodontitis periodontitis
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Hyper-responsive Phenotype in Localized Aggressive Periodontitis
Journal of Dental Research, 01/25/2010
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Shaddox L et al. – Regression analysis demonstrated the hyper–reactive trait to be concomitant expression of pro–inflammatory cyto/chemokines and an absence of anti–inflammatory mediator expression. The ... LAgP cohort, along with an attenuated hyper–responsiveness in healthy siblings, which can be induced in response to multiple TLR ligations.
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Association of Human T Lymphotropic Virus 1 amplification of Periodontitis severity with altered Cytokine expression in response to a standard Periodontopathogen Infection
Clinical Infectious Diseases, 01/13/2010
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Garlet GP et al. – HTLV–1 may play a critical role in the pathogenesis of periodontal disease through the ... exacerbated response against a standard periodontopathogen infection.
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The association of Fcgamma receptor IIIb genetic polymorphism and susceptibility to periodontitis in Taiwanese individuals
Journal of Clinical Periodontology, 01/05/2010
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Ho Y–P et al. – The results of the present study suggest that subjects carrying at least one copy of the FcgammaRIIIb–NA2 allele might be associated with ... polymorphism should be determined by further studies.
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Content Of Urokinase-Type Plasminogen Activator (Upa) And Its Inhibitor PAI-1 In Oral Mucosa And Inflamed Periodontal Tissue
Quintessence International, 01/28/2010
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in the clinically healthy oral mucosa. However, no statistically significant correlation with the sex or age of the patients or attachment loss of the teeth was seen. Serine proteases uPA and its inhibitor PAI–1 participate in periodontitis.
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