Dentistry News & Articles

1 Cell Junction Remodeling in Gingival Tissue Exposed to a Microbial Toxin Journal of Dental Research , May 16, 2013
Damek-Poprawa M et al. - The gingival epithelium plays a key role in protecting the supporting structures of the teeth from bacteria and their products. In ex vivo experiments, authors recently showed that the cytolethal distending toxin (Cdt) from the periodontal pathogen Aggregatibacter actinomycetemcomitans causes extensive damage to gingival tissue. These results indicate that the Cdt induced substantial remodeling of adherens junctions, with a potential impact on the barrier ...

2 Profiling biomarkers in gingival crevicular fluid using multiplex bead immunoassay Archives of Oral Biology, May 8, 2013
Shimada Y et al. - Biomarkers in gingival crevicular fluid (GCF) have been investigated; however, measurements were limited by the small sample volume available. The aim of this study was to determine the levels of 40 different cytokines and chemokines in GCF samples. IL-1{beta} levels in GCF correlate with the PDs, BOP and the presence of P. gingivalis in subgingival plaque. Multiplex bead assays can be useful in GCF studies. These findings can help in identifying new diagnostic ...

3 Soluble Triggering Receptor Expressed on Myeloid Cells (sTREM)-1 in Gingival Crevicular Fluid: Association With Clinical and Microbiological Parameters Journal of Periodontology, May 13, 2013
Belibasakis GN et al. - This cross-sectional study aimed to investigate the levels of sTREM-1 in gingival crevicular fluid (GCF) of non-periodontitis subjects and patients with chronic periodontitis (CP) or generalized aggressive periodontitis (G-AgP), and their association with the levels of key periodontal pathogens in subgingival plaque. The increased GCF levels of sTREM-1 at diseased sites and their positive correlation with clinical and microbiological ...

4 Quantification of elutable substances from methacrylate based sealers and their cytotoxicity effect on with human gingival fibroblasts Dental Materials, May 14, 2013
Furche S et al. - The aim of this study was to investigate the leaching of ingredients from commercial dental fissure sealers as well as their cytotoxic effects on human gingival fibroblast (HGF). Because of the use of sealers in preventative dental medicine it should be taken into account that substances like TEGDMA or CQ, that are often causing allergic reactions, are elutable. Before using the sealers patients should be asked for allergic reactions to these substances.

5 Evaluation of scaling and root planing effect in generalized chronic periodontitis by fractal and multifractal analysis Journal of Periodontal Research, May 15, 2013
Parvu AE et al. - The aim of this work is to assess the structural gingival changes in patients with generalized chronic periodontitis (GCP), before and after scaling and root planing (SRP) by using fractal and multifractal analysis. It has been shown that fractal and multifractal analysis of tissue images as a non-invasive technique could be used to measure contrasting morphologic changes within human gingival cells and tissues and can provide detailed information for ...

6 Immediate implant-supported provisional restoration with a root-form pontic for the replacement of two adjacent anterior maxillary teeth: A clinical report The Journal of Prosthetic Dentistry, May 17, 2013
Schoenbaum TR et al. - In implant therapy, the replacement of 2 adjacent maxillary anterior teeth presents several unique challenges: mesiodistal space constraints, the need to maintain or create natural gingival esthetics, the need for esthetic provisional restorations, and the management of nonaxial forces. The provisional restoration was designed to minimize pressure on the surgical site, optimize space for the gingival tissues, and control occlusal loading of the implant during the ...

7 Gingival Crevicular Fluid, Matrix Metalloproteinases, and Their Bioactive Regulators as Potential Adjunctive Chair-Side Point-of-Care Biomarkers in Orthodontic Tooth Movement Seminars in Orthodontics , February 1, 2013
Ingman T et al. - Variations in levels of different bioactive compounds, including matrix metalloproteinases (MMPs), can be detected in the gingival crevicular fluid (GCF) during orthodontic tooth movement. In this review, the scientific basis of these developments and the potential research and clinical applications of such assays are discussed.

8 Biotype Change for the Esthetic Rehabilitation of the Smile Journal of Esthetic and Restorative Dentistry, May 6, 2013
Polack M et al. - An esthetic and natural appearing smile is the result of multiple important factors. Treatment included management of canines in the lateral incisor positions, proportionally small teeth, and excessive gingival display. Good communication and coordination of care between the surgical and restorative partners produced a pleasing outcome facilitated by periodontal surgery resulting in a modification of the gingival biotype. Smile design including crown lengthening and ...

9 Periodontal status and bacteremia with oral viridans streptococci and coagulase negative staphylococci in allogeneic hematopoietic stem cell transplantation recipients: a prospective observational study Supportive Care in Cancer, May 6, 2013
Raber-Durlacher JE et al. - This study was aimed to investigate whether any association could be found between the presence of an inflamed and infected periodontium (e.g., gingivitis and periodontitis) and the development of bacteremia during neutropenia following allogeneic hematopoietic stem cell transplantation (HSCT). This study indicates that periodontal infections may contribute to the risk of developing OVS and CONS bacteremia during neutropenia following HSCT. While the ...

10 Calcitonin gingival crevicular fluid levels and pain discomfort during early orthodontic tooth movement in young patients Archives of Oral Biology, May 8, 2013
Alarcon JA et al. - To investigate the previously unreported presence of calcitonin (CT) levels in gingival crevicular fluid (GCF), its variations during initial orthodontic tooth movement in both tension and compression sites, and its possible association with the experienced dental pain. CT levels in the GCF significantly increased in the compression site after the short term after application of orthodontic forces. These changes were negatively associated with the perceived patient's ...