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Nikitakis NG et al. - The data indicate an almost universal expression of activated Stat3 and survivin in benign and malignant SGTs. Considering the well established proliferative and antiapoptotic properties of these molecules and their functional interrelationship, selective targeting techniques against Stat3 and/or survivin may represent promising therapeutic strategies against neoplasms of salivary gland origin.

Today in Basic Science...keeping you current

Overexpression of Kif2a promotes the progression and metastasis of squamous cell carcinoma of the oral tongue
Oral Oncology , 12/16/09

Inhibition of Apoptosis in Periodontitis
Journal of Dental Research , 12/16/09

De novo mutation in the DSPP gene associated with dentinogenesis imperfecta type II in a Japanese family
European Journal of Oral Sciences, 11/19/09