MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
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1 Relationship between chronic obstructive pulmonary disease and subclinical coronary artery disease in long-term smokers European Heart Journal – Cardiovascular Imaging, May 20, 2013 Clinical Article
2 Hyperhomocysteinemia is an independent risk factor in young patients with coronary artery disease in southern China Herz, May 20, 2013 Clinical Article
3 The ability of NT-proBNP to detect chronic heart failure and predict all-cause mortality is higher in elderly Chinese coronary artery disease patients with chronic kidney disease Full Text Clinical Interventions in Aging, May 20, 2013 Review Article
4 The shared allelic architecture of adiponectin levels and coronary artery disease Atherosclerosis, May 20, 2013 Clinical Article
5 Clopidogrel resistance in North Indian patients of coronary artery disease and lack of its association with platelet ADP receptors P2Y1 and P2Y12 gene polymorphisms Platelets, May 20, 2013 Clinical Article
6 Improved Accuracy of Myocardial Perfusion SPECT for the Detection of Coronary Artery Disease Using a Support Vector Machine Algorithm The Journal of Nuclear Medicine, May 20, 2013 Clinical Article
7 Variations in matrix metalloproteinase-1, -3, and -9 genes and the risk of acute coronary syndrome and coronary artery disease in the Chinese Han population Coronary Artery Disease, May 20, 2013 Clinical Article
8 Beneficial effects of polyphenol-rich olive oil in patients with early atherosclerosis European Journal of Nutrition, May 20, 2013 Clinical Article
9 Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study Annals of Rheumatic Diseases, May 20, 2013 Clinical Article
10 The Value of Carotid Artery Plaque and Intima-Media Thickness for Incident Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis Full Text Journal of the American Heart Association, May 20, 2013 Clinical Article
11 Low serum pancreatic enzyme levels predict mortality and are associated with malnutrition-inflammation-atherosclerosis syndrome in patients with chronic kidney disease International Urology and Nephrology, May 20, 2013 Clinical Article
12 Impact of polyvascular disease on clinical outcomes in patients undergoing coronary revascularization: An observation from the CREDO-Kyoto Registry Cohort-2 Atherosclerosis, May 10, 2013 Clinical Article
13 Preprocedural statin therapy, inflammation and myocardial injury in low-risk stable coronary artery disease patients submitted to coronary stent implantation Catheterization and Cardiovascular Interventions, May 10, 2013 Clinical Article
14 Cost-effectiveness analysis of coronary artery disease screening in HIV-infected men European Journal of Preventive Cardiology, May 10, 2013 Clinical Article
15 Diagnostic accuracy of 320-slice computed tomography angiography for detection of coronary artery stenosis: Meta-analysis International Journal of Cardiology, May 10, 2013 Evidence Based Medicine Review Article
16 Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes Full Text Cardiovascular Diabetology, May 10, 2013 Review Article
17 Feasibility of coronary artery wall thickening assessment in asymptomatic coronary artery disease using phase-sensitive dual-inversion recovery MRI at 3T Magnetic Resonance Imaging, May 10, 2013 Clinical Article
18 Home-based secondary prevention programs for patients with coronary artery disease: a meta-analysis of effects on anxiety Journal of Cardiopulmonary Rehabilitation and Prevention, May 10, 2013 Evidence Based Medicine Review Article
19 Predictive value of brachial reactive hyperemia and flow-mediated dilation in stable coronary artery disease Clinical Hemorheology and Microcirculation, May 10, 2013 Review Article
20 Cost-effectiveness of a coronary heart disease secondary prevention program in patients with myocardial infarction: results from a randomised controlled trial Full Text BMC Cardiovascular Disorders, May 10, 2013 Clinical Article
21 Factors underlying regression of coronary atheroma with potent statin therapy European Heart Journal, May 10, 2013 Clinical Article
22 Omega-3 Polyunsaturated Fatty Acids Increase Plasma Adiponectin to Leptin Ratio in Stable Coronary Artery Disease Cardiovascular Drugs and Therapy, April 30, 2013 Clinical Article
23 Prevalence and severity of asymptomatic coronary and carotid artery disease in patients with lower limbs arterial disease Atherosclerosis, April 30, 2013 Clinical Article
24 Is Risk Factor Control and Guideline-Based Medical Therapy Optimal in Patients With Nonobstructive Coronary Artery Disease? A Veterans Affairs Study The American Journal of the Medical Sciences, April 30, 2013 Clinical Article
25 Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons Clinical Infectious Diseases, April 30, 2013 Clinical Article
26 Combined non-invasive functional and anatomical diagnostic work-up in clinical practice: the magnetic resonance and computed tomography in suspected coronary artery disease (MARCC) study European Heart Journal, April 30, 2013 Clinical Article
27 Discordant effects of rosiglitazone on novel inflammatory biomarkers American Heart Journal, April 30, 2013 Clinical Article
28 Interactions between inflammation and lipid metabolism: Relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis Atherosclerosis, April 30, 2013 Review Article
29 Effect of Insulin Glargine and n-3FA on Carotid Intima-Media Thickness in People With Dysglycemia at High Risk for Cardiovascular Events: The Glucose Reduction and Atherosclerosis Continuing Evaluation Study (ORIGIN-GRACE) Diabetes Care, April 30, 2013 Clinical Article
30 Coronary endothelial dysfunction in patients with early coronary artery disease is associated with the increase in intravascular lipid core plaque European Heart Journal, April 30, 2013 Clinical Article
31 Effect Of Hypolipidemic Treatment On Emerging Risk Factors In Mixed Dyslipidemia: A Randomized Pilot Trial European Journal of Clinical Investigation, April 30, 2013 Clinical Article
32 Long term survival in elderly patients with stable coronary disease European Journal of Clinical Investigation, April 20, 2013 Clinical Article
33 Significant Coronary Stenosis in Asymptomatic Chinese With Different Glycemic Status Diabetes Care, April 20, 2013 Review Article
34 Atherosclerotic Changes in Common Carotid Artery, Common Femoral Artery, and Ascending Aorta/Aortic Arch in Candidates for Coronary Artery Bypass Graft Surgery Angiology, April 20, 2013 Clinical Article
35 The worrisome liaison between left ventricular systolic dysfunction and mitral annulus calcification in type 2 diabetes without coronary artery disease: Data from the SHORTWAVE study Nutrition, Metabolism & Cardiovascular Diseases, April 20, 2013 Clinical Article
36 Inhibition of the renin–angiotensin system for lowering coronary artery disease risk Current Opinion in Pharmacology , April 20, 2013 Review Article
37 Hematological parameters and coronary collateral circulation in patients with stable coronary artery disease Full Text Experimental and Clinical Cardiology, April 20, 2013 Clinical Article
38 Metabolic syndrome is not a predictor for cardiovascular events in Japanese patients with diabetes mellitus asymptomatic for coronary artery disease: A retrospective analysis of the J-ACCESS-2 study Journal of Nuclear Cardiology, April 20, 2013 Clinical Article
39 Family history of coronary heart disease and markers of subclinical cardiovascular disease: Where do we stand Atherosclerosis, April 20, 2013 Review Article
40 Epicardial Adipose Tissue Volume and Adipocytokine Imbalance Are Strongly Linked to Human Coronary Atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology, April 20, 2013 Clinical Article
41 CT vs SPECT: CT is the first-line test for the diagnosis and prognosis of stable coronary artery disease Journal of Nuclear Cardiology, April 20, 2013 Clinical Article
42 Impact of Concomitant Coronary Artery Disease on Atherosclerotic Plaques in the Aortic Arch in Patients With Severe Aortic Stenosis Full Text Clinical Cardiology, April 20, 2013 Clinical Article
43 Prognostic Value of Cardiac Troponin I Measured With a Highly Sensitive Assay in Patients With Stable Coronary Artery Disease JACC - Journal of the American College of Cardiology, April 10, 2013 Clinical Article
44 Impact of Family History of Coronary Artery Disease in Young Individuals (from the CONFIRM Registry) The American Journal of Cardiology, April 10, 2013 Clinical Article
45 Elevated Rho-Kinase Activity as a Marker Indicating Atherosclerosis and Inflammation Burden in Polyvascular Disease Patients With Concomitant Coronary and Peripheral Arterial Disease Full Text Clinical Cardiology, April 10, 2013 Clinical Article
46 Carotid Intima-Media Thickness and Carotid Plaques Improves Prediction of Obstructive Angiographic Coronary Artery Disease in Women Angiology, April 10, 2013 Clinical Article
47 Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis International Journal of Cardiology, April 10, 2013 Clinical Article
48 Differential impact of metabolic syndrome on subclinical atherosclerosis according to the presence of diabetes Full Text Cardiovascular Diabetology, April 10, 2013 Clinical Article
49 Bioabsorbable scaffolds for the treatment of obstructive coronary artery disease: the next revolution in coronary intervention? Heart, April 10, 2013 Review Article
50 Carotid Artery Plaque and Progression of Coronary Artery Calcium: The Multi-Ethnic Study of Atherosclerosis Journal of the American Society of Echocardiography, April 10, 2013 Clinical Article
51 Hypercortisolism Is Associated With Increased Coronary Arterial Atherosclerosis: Analysis of Noninvasive Coronary Angiography Using Multidetector Computerized Tomography Journal of Clinical Endocrinology and Metabolism, April 10, 2013 Clinical Article
52 Chronic kidney disease -- Is it a true risk factor of reduced clopidogrel efficacy in elderly patients with stable coronary artery disease? Thrombosis Research, March 31, 2013 Evidence Based Medicine Clinical Article
53 Combined non-invasive functional and anatomical diagnostic work-up in clinical practice: the magnetic resonance and computed tomography in suspected coronary artery disease (MARCC) study European Heart Journal, March 31, 2013 Clinical Article
54 Prognostic Implications of Nonobstructive Coronary Artery Disease in Patients Undergoing Coronary Computed Tomographic Angiography for Acute Chest Pain The American Journal of Cardiology, March 31, 2013 Clinical Article
55 Low high-density lipoprotein cholesterol is a residual risk factor associated with long-term clinical outcomes in diabetic patients with stable coronary artery disease who achieve optimal control of low-density lipoprotein cholesterol Heart and Vessels, March 31, 2013 Clinical Article
56 Accuracy of Stress Myocardial Perfusion Imaging to Diagnose Coronary Artery Disease in End Stage Liver Disease Patients The American Journal of Cardiology, March 31, 2013 Clinical Article
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Diagnosis and management of carotid atherosclerosis
British Medical Journal, March 31, 2013
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58 Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations The Lancet, March 31, 2013 Clinical Article
59 Circulating Vitamin D Metabolites and Subclinical Atherosclerosis in Type 1 Diabetes Diabetes Care, March 31, 2013 Clinical Article
60 Niacin Administration Significantly Reduces Oxidative Stress in Patients With Hypercholesterolemia and Low Levels of High-Density Lipoprotein Cholesterol The American Journal of the Medical Sciences, March 31, 2013 Clinical Article
61 Effect of physical activity on heart rate variability and carotid intima-media thickness in older people Internal and Emergency Medicine, March 31, 2013 Clinical Article
62 Therapeutic gene targeting approaches for the treatment of dyslipidemias and atherosclerosis Current Opinion in Lipidology, March 31, 2013 Review Article Clinical Article
63 Association Between the Chromosome 9p21 Locus and Angiographic Coronary Artery Disease Burden A Collaborative Meta-Analysis JACC - Journal of the American College of Cardiology, March 21, 2013 Evidence Based Medicine Review Article
64 Association of retinopathy with coronary atherosclerosis determined by coronary 64-slice multidetector computed tomography angiography in type 2 diabetes Diabetes & Vascular Disease Research, March 21, 2013 Review Article
65 Coronary plaque component in patients with vasospastic angina: A virtual histology intravascular ultrasound study International Journal of Cardiology, March 21, 2013 Clinical Article
66 Long-Term Use of Lipid-Lowering Drugs Slows Progression of Carotid AtherosclerosisSignificance Arteriosclerosis, Thrombosis, and Vascular Biology, March 21, 2013 Clinical Article
67 Early Detection of Subclinical Atherosclerosis in Asymptomatic Patients Assessed by Carotid Duplex and Coronary Computed Tomography Full Text International Journal of Gerontology, March 21, 2013 Review Article
68 Association of thyroid stimulating hormone levels with subclinical carotid atherosclerosis in a Mediterranean female population Cardiovascular Endocrinology, March 21, 2013 Clinical Article
69 Atherosclerosis across 4000 years of human history: the Horus study of four ancient populations The Lancet, March 21, 2013 Evidence Based Medicine
70 Comparison of Change in Coronary Atherosclerosis in Patients With Stable Versus Unstable Angina Pectoris Receiving Statin Therapy (from the Treatment With Statin on Atheroma Regression Evaluated by Intravascular Ultrasound With Virtual Histology [TRUTH] Study) The American Journal of Cardiology, March 21, 2013 Clinical Article
71 Metabolic syndrome in healthy obese, overweight, and normal weight individuals: The atherosclerosis risk in communities study Obesity, March 21, 2013 Review Article
72 Discordance between Framingham Risk Score and atherosclerotic plaque burden European Heart Journal, March 11, 2013 Clinical Article
73 Prevalence of Regional Myocardial Thinning and Relationship With Myocardial Scarring in Patients With Coronary Artery Disease JAMA, March 11, 2013 Clinical Article
74 A Risk Score for Predicting Coronary Artery Disease in Women With Angina Pectoris and Abnormal Stress Test Finding The American Journal of Cardiology, March 11, 2013 Clinical Article
75 Non-invasive assessment of microcirculation by sidestream dark field imaging as a marker of coronary artery disease in diabetes Diabetes & Vascular Disease Research, March 11, 2013 Review Article
76 Earlobe Crease May Provide Predictive Information on Asymptomatic Peripheral Arterial Disease in Patients Clinically Free of Atherosclerotic Vascular Disease Angiology, March 11, 2013 Clinical Article
77 Postmenopausal women with carotid atherosclerosis: Potential role of the serum calcium levels Nutrition, Metabolism & Cardiovascular Diseases, March 11, 2013 Clinical Article
78 Utility of an Advanced Digital Electronic Stethoscope in the Diagnosis of Coronary Artery Disease Compared With Coronary Computed Tomographic Angiography The American Journal of Cardiology, March 11, 2013 Clinical Article
79 Coronary artery disease in patients clinically diagnosed with myocardial infarction in the medical intensive care unit Journal of Critical Care, March 1, 2013 Clinical Article
80 Effects of statin treatment in patients with coronary artery disease and chronic kidney disease Heart and Vessels, March 1, 2013 Clinical Article
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryAs published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryAs published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summary1 Effect of Metoprolol Versus Carvedilol on Outcomes in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) JACC - Journal of the American College of Cardiology, April 3, 2013
2 Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry American Heart Journal, April 1, 2013
3 The long QT syndrome: a transatlantic clinical approach to diagnosis and therapy European Heart Journal, April 9, 2013 Review Article
4 Effect of coenzyme q10 supplementation on statin-induced myalgias The American Journal of Cardiology, July 30, 2012
5 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013
6 Statins and autoimmunity Immunologic Research, April 17, 2013 Review Article
7 Meta-Analysis of Carvedilol Versus Beta 1 Selective Beta-Blockers (Atenolol, Bisoprolol, Metoprolol, and Nebivolol) The American Journal of Cardiology, February 26, 2013 Evidence Based Medicine Review Article
8 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
9 Clinical Update on the Management of Atrial Fibrillation Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 10, 2013
10 Treatment of Hypertension Among African Americans: The Jackson Heart Study The Journal of Clinical Hypertension, April 5, 2013
11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013
12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article
13 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article
14 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article
15 Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient International Journal of General Medicine, April 2, 2013 Free full text
16 Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study JACC - Journal of the American College of Cardiology, April 12, 2013
17 Combination therapy in the management of pulmonary arterial hypertension International Journal of Clinical Practice, April 15, 2013 Review Article
18 A double-blind, double-dummy, randomized, placebo-controlled trial to evaluate the effect of statin therapy on triglyceride levels in Mexican hypertriglyceridemic patients Current Medical Research and Opinion, April 16, 2013
19 Long-term clinical follow-up of the multicenter, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES) European Heart Journal, April 11, 2013
20 Can Vitamin D Supplementation Improve the Severity of Congestive Heart Failure? Congestive Heart Failure, April 2, 2013 Free full text
Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
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