MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
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1 Prealbumin improves death risk prediction of BNP-added Seattle Heart Failure Model: Results from a pilot study in elderly chronic heart failure patients International Journal of Cardiology, May 21, 2013 Clinical Article
2 Early and personalized ambulatory follow-up to tailor furosemide and fluid intake according to congestion in post-discharge heart failure Internal and Emergency Medicine, May 21, 2013 Clinical Article
3 Chronic elevation of pulmonary microvascular pressure in chronic heart failure reduces bi-directional pulmonary fluid flux European Journal of Heart Failure, May 21, 2013 Clinical Article
4 Immunosenescence-associated microRNAs in age and heart failure European Journal of Heart Failure, May 21, 2013 Clinical Article
5 Usefulness of Albuminuria as a Prognostic Indicator in Patients With Chronic Heart Failure Secondary to Ischemic or Idiopathic Dilated Cardiomyopathy The American Journal of Cardiology, May 21, 2013 Clinical Article
6 Prognostic relevance of a non-invasive evaluation of right ventricular function and pulmonary artery pressure in patients with chronic heart failure European Journal of Heart Failure, May 21, 2013 Clinical Article
7 Effects of Tai Chi training on exercise capacity and quality of life in patients with chronic heart failure: a meta-analysis European Journal of Heart Failure, May 21, 2013 Evidence Based Medicine
8 Physiological response to the 6-minute walk test in chronic heart failure patients versus healthy control subjects European Journal of Preventive Cardiology, May 21, 2013 Clinical Article
9 An abnormal apelin/vasopressin balance may contribute to water retention in patients with the syndrome of inappropriate antidiuretic hormone (SIADH) and heart failure Journal of Clinical Endocrinology and Metabolism, May 21, 2013 Clinical Article
10 Prognostic utility of the Seattle Heart Failure Score and amino terminal pro B-type natriuretic peptide in varying stages of systolic heart failure The Journal of Heart and Lung Transplantation, May 21, 2013 Review Article
11 Independent Role of Left Ventricular Global Longitudinal Strain in Predicting Prognosis of Chronic Heart Failure Patients Echocardiography, May 21, 2013 Clinical Article
12 Therapeutic Potential of Tumour Necrosis Factor-alpha Antagonists in Patients with Chronic Heart Failure Heart, Lung, and Circulation, May 21, 2013 Review Article
13 Expression of miR-126 and miR-508-5p in endothelial progenitor cells is associated with the prognosis of chronic heart failure patients International Journal of Cardiology, May 21, 2013 Clinical Article
14 Exercise-resembling effects of periodic somatosensory stimulation in heart failure International Journal of Cardiology, May 11, 2013 Clinical Article
15 Insomnia and the risk of incident heart failure: a population study European Heart Journal, May 11, 2013 Clinical Article
16 Long-term impact of cardiac resynchronization therapy in mild heart failure: 5-year results from the REsynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (REVERSE) study European Heart Journal, May 11, 2013 Clinical Article
17 Chronic heart failure and risk of hospitalization with pneumonia: A population-based study European Journal of Internal Medicine , May 11, 2013 Clinical Article
18 Ace inhibitor therapy for heart failure in patients with impaired renal function: a review of the literature Heart Failure Reviews, May 11, 2013 Clinical Article
19 Cardiohepatic Interactions in Heart Failure: An Overview and Clinical Implications JACC - Journal of the American College of Cardiology, May 1, 2013 Clinical Article
20 U-Shape Association Between Hemoglobin A1c and Late Mortality in Patients With Heart Failure After Cardiac Surgery The American Journal of Cardiology, May 1, 2013 Clinical Article
21 Hepatic Dysfunction in Ambulatory Patients with Heart Failure - Application of the MELD Scoring System for Outcome Prediction JACC - Journal of the American College of Cardiology, May 1, 2013 Clinical Article
22 Patients with New York Heart Association class III heart failure may benefit with high flow nasal cannula supportive therapy: High flow nasal cannula in heart failure Journal of Critical Care, May 1, 2013 Clinical Article
23 Echocardiographic Left Ventricular End-Diastolic Pressure Volume Loop Estimate Predicts Survival in Congestive Heart Failure Journal of Cardiac Failure, May 1, 2013 Review Article
24 Hyponatremia and In-Hospital Mortality in Patients Admitted for Heart Failure (from the ATTEND Registry) The American Journal of Cardiology, May 1, 2013 Clinical Article
25 Prediction of all-cause mortality and heart failure admissions from global left ventricular longitudinal strain in patients with acute myocardial infarction and preserved left ventricular ejection fraction JACC - Journal of the American College of Cardiology, May 1, 2013 Clinical Article
26 Comparison of Medication Practices in Patients With Heart Failure and Preserved Versus Those With Reduced Ejection Fraction (from the Cardiovascular Research Network [CVRN]) The American Journal of Cardiology, May 1, 2013 Clinical Article
27 Contemporary Prevalence and Correlates of Incident Heart Failure with Preserved Ejection Fraction American Journal of Medicine, May 1, 2013 Review Article
28 Predictors of Incident Heart Failure Hospitalizations Among Patients With Impaired Glucose Tolerance Circulation: Heart Failure, May 1, 2013 Clinical Article
29 Can Vitamin D Supplementation Improve the Severity of Congestive Heart Failure? Full Text Congestive Heart Failure, April 21, 2013 Clinical Article
30 Midterm Effects and Clinical Benefits of Left Ventricular vs Biventricular Pacing in Heart Failure Canadian Journal of Cardiology, April 21, 2013 Clinical Article
31 Efficacy and safety of bisoprolol fumarate compared with carvedilol in Japanese patients with chronic heart failure: results of the randomized, controlled, double-blind, Multistep Administration of bisoprolol IN Chronic Heart Failure II (MAIN-CHF II) study Heart and Vessels, April 21, 2013 Clinical Article
32 Body mass index, gender, and clinical outcome among hypertensive and diabetic patients with stage A/B heart failure Obesity, April 21, 2013 Review Article
33 Long-Term Outcomes in Elderly Survivors of In-Hospital Cardiac Arrest New England Journal of Medicine, April 21, 2013 Clinical Article
34 Current management and future directions for the treatment of patients hospitalized for heart failure with low blood pressure Heart Failure Reviews, April 21, 2013 Review Article
35 Treatment of Severe Metabolic Alkalosis in a Patient With Congestive Heart Failure American Journal of Kidney Diseases, April 21, 2013
36 Long-Chain Monounsaturated Fatty Acids and Incidence of Congestive Heart Failure in 2 Prospective Cohorts Circulation, April 21, 2013 Clinical Article
37 Myths and Facts About Heart Failure with Preserved Ejection Fraction: Risk Factors, Longevity, Potential Pharmacological and Exercise Interventions Full Text International Journal of Gerontology, April 21, 2013 Review Article
38 Blood Urea Nitrogen/Creatinine Ratio Identifies a High-Risk but Potentially Reversible Form of Renal Dysfunction in Patients With Decompensated Heart Failure Circulation: Heart Failure, April 21, 2013 Review Article
39 Effect of Spironolactone on Diastolic Function and Exercise Capacity in Patients With Heart Failure With Preserved Ejection FractionThe Aldo-DHF Randomized Controlled Trial JAMA, April 11, 2013 Clinical Article
40 Treatment of Anemia with Darbepoetin Alfa in Systolic Heart Failure New England Journal of Medicine, April 11, 2013 Clinical Article
41 Iron deficiency in chronic heart failure: An international pooled analysis American Heart Journal, April 11, 2013 Clinical Article
42 Predictors of New-Onset Heart Failure Circulation: Heart Failure, April 11, 2013 Clinical Article
43 B-Type Natriuretic Peptide and Prognosis in Heart Failure Patients With Preserved and Reduced Ejection Fraction Full Text JACC - Journal of the American College of Cardiology, April 11, 2013 Clinical Article
44 Risk-Benefit Profile of Warfarin Versus Aspirin in Patients With Heart Failure and Sinus Rhythm: A Meta-analysis Circulation: Heart Failure, April 11, 2013 Evidence Based Medicine Review Article Clinical Article
45 Cardiorenal Anemia Syndrome as a Prognosticator for Death in Heart Failure The American Journal of Cardiology, April 11, 2013 Clinical Article
46 Association Between Bilirubin and Mode of Death in Severe Systolic Heart Failure The American Journal of Cardiology, April 11, 2013 Clinical Article
47 Importance of the time of initiation of mineralocorticoid receptor antagonists on risk of mortality in patients with heart failure Journal of the Renin-Angiotensin-Aldosterone System, April 11, 2013 Clinical Article
48 Carotid body removal for treatment of chronic systolic heart failure International Journal of Cardiology, April 11, 2013 Clinical Article
49 Development and validation of an integrated diagnostic algorithm derived from parameters monitored in implantable devices for identifying patients at risk for heart failure hospitalization in an ambulatory setting European Heart Journal, April 11, 2013 Clinical Article
50 Multiparametric comparison of CARvedilol, vs. NEbivolol, vs. BIsoprolol in moderate heart failure: The CARNEBI trial International Journal of Cardiology, April 1, 2013 Clinical Article
51 Early Identification of Asymptomatic Subjects at Increased Risk of Heart Failure and Cardiovascular Events: Progress and Future Directions Heart, Lung, and Circulation, April 1, 2013 Review Article
52 Association of Spironolactone Use With All-Cause Mortality in Heart Failure Circulation: Heart Failure, April 1, 2013 Clinical Article
53 Predictors and prognostic implications of incident heart failure following the first diagnosis of atrial fibrillation in patients with structurally normal hearts: the Belgrade Atrial Fibrillation Study European Heart Journal, April 1, 2013 Clinical Article
54 Effectiveness of (beta)-Blockers in Heart Failure With Left Ventricular Systolic Dysfunction and Chronic Kidney Disease Journal of Cardiac Failure, April 1, 2013 Clinical Article
55 Intermittent levosimendan treatment in patients with severe congestive heart failure Clinical Research in Cardiology, April 1, 2013 Clinical Article
56 Acute Effects of Withdrawal of Cardiac Resynchronization Therapy on Left and Right Ventricular Function, Dyssynchrony, and Contractile Function in Patients With New York Heart Association Functional Class I/II Heart Failure: MADIT-CRT Journal of Cardiac Failure, April 1, 2013 Clinical Guideline Clinical Article
57 Fatty acid-binding protein 4 and incident heart failure: the Cardiovascular Health Study European Journal of Heart Failure, April 1, 2013 Clinical Article
58 Predictors of early dyspnoea relief in acute heart failure and the association with 30-day outcomes: findings from ASCEND-HF European Journal of Heart Failure, April 1, 2013 Clinical Article
59
Benefits of β blockers in patients with heart failure and reduced ejection fraction: network meta-analysis
British Medical Journal, March 22, 2013
Evidence Based Medicine
Review Article
Exclusive Author Commentary
60 Efficacy and safety of warfarin vs. antiplatelet therapy in patients with systolic heart failure and sinus rhythm: a systematic review and meta-analysis of randomized controlled trials International Journal of Stroke, March 22, 2013 Clinical Article
61 Effect of Aliskiren on Postdischarge Mortality and Heart Failure Readmissions Among Patients Hospitalized for Heart Failure: The ASTRONAUT Randomized Trial JAMA, March 22, 2013 Clinical Article
62 Treatment of Anemia with Darbepoetin Alfa in Systolic Heart Failure New England Journal of Medicine, March 22, 2013 Clinical Article
63 A Randomized Trial to Assess Catheter Ablation versus Rate Control in the Management of Persistent Atrial Fibrillation in Heart Failure (ARC-HF) JACC - Journal of the American College of Cardiology, March 22, 2013 Clinical Article
64 Relation of B-Type Natriuretic Peptide Level in Heart Failure to Sudden Cardiac Death in Patients With and Without QT Interval Prolongation The American Journal of Cardiology, March 22, 2013
65 The missed opportunities to diagnose and treat iron deficiency in patients hospitalized with heart failure International Journal of Cardiology, March 22, 2013 Clinical Article
66 Incidence and predictors of heart failure hospitalization and death in permanent pacemaker patients: a single-centre experience over medium-term follow-up EP Europace, March 22, 2013 Clinical Article
67 Prognostic Values of Serum Tenascin-C in Patients with Ischaemic Heart Disease and Heart Failure Heart, Lung, and Circulation, March 22, 2013 Clinical Article
68 Effect of Spironolactone on Diastolic Function and Exercise Capacity in Patients With Heart Failure With Preserved Ejection Fraction: The Aldo-DHF Randomized Controlled Trial JAMA, March 12, 2013 Clinical Article
69 Diabetes mellitus is associated with adverse prognosis in chronic heart failure of ischaemic and non-ischaemic aetiology Diabetes & Vascular Disease Research, March 12, 2013 Clinical Article
70 Androgen modulates cardiac fibrosis contributing to gender differences on heart failure The Aging Male, March 12, 2013 Review Article
71 Relationship between Left Atrial Function and Size and Level of Left Ventricular Dyssynchrony in Heart Failure Patients Echocardiography, March 12, 2013 Clinical Article
72 Plasma phospholipid trans fatty acids and risk of heart failure American Journal of Clinical Nutrition, March 12, 2013 Clinical Article
73 Effect of bucindolol on heart failure outcomes and heart rate response in patients with reduced ejection fraction heart failure and atrial fibrillation European Journal of Heart Failure, March 2, 2013 Clinical Article
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryAs published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryAs published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summary1 Effect of Metoprolol Versus Carvedilol on Outcomes in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) JACC - Journal of the American College of Cardiology, April 3, 2013
2 Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry American Heart Journal, April 1, 2013
3 The long QT syndrome: a transatlantic clinical approach to diagnosis and therapy European Heart Journal, April 9, 2013 Review Article
4 Effect of coenzyme q10 supplementation on statin-induced myalgias The American Journal of Cardiology, July 30, 2012
5 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013
6 Statins and autoimmunity Immunologic Research, April 17, 2013 Review Article
7 Meta-Analysis of Carvedilol Versus Beta 1 Selective Beta-Blockers (Atenolol, Bisoprolol, Metoprolol, and Nebivolol) The American Journal of Cardiology, February 26, 2013 Evidence Based Medicine Review Article
8 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
9 Clinical Update on the Management of Atrial Fibrillation Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 10, 2013
10 Treatment of Hypertension Among African Americans: The Jackson Heart Study The Journal of Clinical Hypertension, April 5, 2013
11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013
12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article
13 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article
14 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article
15 Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient International Journal of General Medicine, April 2, 2013 Free full text
16 Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study JACC - Journal of the American College of Cardiology, April 12, 2013
17 Combination therapy in the management of pulmonary arterial hypertension International Journal of Clinical Practice, April 15, 2013 Review Article
18 A double-blind, double-dummy, randomized, placebo-controlled trial to evaluate the effect of statin therapy on triglyceride levels in Mexican hypertriglyceridemic patients Current Medical Research and Opinion, April 16, 2013
19 Long-term clinical follow-up of the multicenter, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES) European Heart Journal, April 11, 2013
20 Can Vitamin D Supplementation Improve the Severity of Congestive Heart Failure? Congestive Heart Failure, April 2, 2013 Free full text
Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
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