MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
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981 Effect of Allopurinol on Blood Pressure: A Systematic Review and Meta-Analysis The Journal of Clinical Hypertension, August 22, 2012 Evidence Based Medicine Clinical Article
982 The adipokine visfatin induces tissue factor expression in human coronary artery endothelial cells: Another piece in the adipokines puzzle Thrombosis Research, August 22, 2012 Clinical Article
983 Vascular Effects of Nebivolol Added to Hydrochlorothiazide in African Americans With Hypertension and Echocardiographic Evidence of Diastolic Dysfunction The NASAA Study Journal of Cardiovascular Pharmacology and Therapeutics, August 22, 2012 Evidence Based Medicine Clinical Article
984 Statin-Induced Low Cholesterol is Not Associated With Poor Outcome in Chronic Heart Failure Journal of Cardiovascular Pharmacology and Therapeutics, August 21, 2012 Clinical Article
985 Fixed-Dose Combination Therapy in Hypertension High Blood Pressure & Cardiovascular Prevention, August 21, 2012 Clinical Article
986 An Observational, Prospective, Open-Label, Multicentre Evaluation of Aliskiren in Treated, Uncontrolled Patients: A Real-Life, Long-Term, Follow-Up, Clinical Practice in Italy High Blood Pressure & Cardiovascular Prevention, August 21, 2012 Clinical Article
987 Acute responses to inhalation of Iloprost in patients with pulmonary hypertension Full Text Chinese Medical Journal, August 21, 2012 Clinical Article
988 Effect of Rosuvastatin on the Echolucency of the Common Carotid Intima-Media in Low-Risk Individuals: The METEOR Trial Journal of the American Society of Echocardiography, August 20, 2012 Clinical Article
989 Triple antithrombotic therapy in patients with atrial fibrillation who have undergone percutaneous coronary intervention with stent implantation American Journal of Health-System Pharmacy, August 20, 2012 Evidence Based Medicine Clinical Article
990 A new epoprostenol formulation for the treatment of pulmonary arterial hypertension American Journal of Health-System Pharmacy, August 20, 2012 Clinical Article
991 Meta-Analysis Comparing Bivalirudin Versus Heparin Monotherapy on Ischemic and Bleeding Outcomes After Percutaneous Coronary Intervention The American Journal of Cardiology, August 17, 2012 Evidence Based Medicine Clinical Article
992 β Blockers for Prevention of Exercise-Induced Left Ventricular Outflow Tract Obstruction in Patients With Hypertrophic Cardiomyopathy The American Journal of Cardiology, August 17, 2012 Clinical Article
993 Intervention to Improve Adherence to Lipid-Lowering Medication and Lipid-Levels in Patients With an Increased Cardiovascular Risk The American Journal of Cardiology, August 17, 2012 Clinical Article
994 Pro-apoptotic effects of imatinib on PDGF-stimulated pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension International Journal of Cardiology, August 17, 2012 Clinical Article
995 Formulation parameters influencing the physicochemical characteristics of rosiglitazone-loaded cationic lipid emulsion Full Text Archives of Pharmacal Research, August 17, 2012 Clinical Article
996 Comparison of Effectiveness of Ranolazine Plus Amiodarone Versus Amiodarone Alone for Conversion of Recent-Onset Atrial Fibrillation The American Journal of Cardiology, August 16, 2012 Clinical Article
997 Comparative Effectiveness Analysis of Amlodipine/Renin-Angiotensin System Blocker Combinations The Journal of Clinical Hypertension, August 16, 2012 Clinical Article
998 Eplerenone is not superior to older and less expensive aldosterone antagonists American Journal of Medicine, August 16, 2012 Clinical Article
999 Interference of NSAIDs with the thrombocyte inhibitory effect of aspirin: A placebo-controlled, ex vivo, serial placebo-controlled serial crossover study European Journal of Clinical Pharmacology, August 16, 2012 Clinical Article
1000 Impaired bioavailability and antiplatelet effect of high-dose clopidogrel in patients after cardiopulmonary resuscitation (CPR) European Journal of Clinical Pharmacology, August 16, 2012 Clinical Article
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryAs published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryAs published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summary1 Statins and autoimmunity Immunologic Research, April 17, 2013 Review Article
2 Treatment of Anemia with Darbepoetin Alfa in Systolic Heart Failure New England Journal of Medicine, April 2, 2013
3 Beyond Statins: Lipid Management to Reduce Cardiovascular Risk Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 29, 2013 Evidence Based Medicine Review Article
4 Efficacy and Effects on Lipid Metabolism of Combination Treatment With Losartan + Hydrochlorothiazide Versus Losartan + Amlodipine: A 48-Week Prospective, Multicenter, Randomized, Open-Label Trial Clinical Therapeutics, April 23, 2013
5 Clinical Update on the Management of Atrial Fibrillation Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 10, 2013
6 Efficacy and safety of bisoprolol fumarate compared with carvedilol in Japanese patients with chronic heart failure: results of the randomized, controlled, double-blind, Multistep Administration of bisoprolol IN Chronic Heart Failure II (MAIN-CHF II) study Heart and Vessels, April 9, 2013
7 Risk-Benefit Profile of Warfarin Versus Aspirin in Patients With Heart Failure and Sinus Rhythm: A Meta-analysis Circulation: Heart Failure, April 3, 2013 Evidence Based Medicine Review Article
8 The Efficacy of Guanxinning Injection in Treating Angina Pectoris: Systematic Review and Meta-Analysis of Randomized Controlled Trials Evidence-based Complementary and Alternative Medicine , April 11, 2013 Free full text Evidence Based Medicine Review Article
9 Systematic Review of CETP Inhibitors for Increasing High-Density Lipoprotein Cholesterol: Where Do These Agents Stand in the Approval Process? American Journal of Therapeutics, April 25, 2013 Evidence Based Medicine Review Article
10 Review of Economics and Cost-Effectiveness Analyses of Anticoagulant Therapy for Stroke Prevention in Atrial Fibrillation in the US Annals of Pharmacotherapy, April 23, 2013 Review Article
11 Dual Anti-platelet Therapy After Coronary Artery Bypass Grafting: Is There Any Benefit? A Systematic Review and Meta-Analysis Journal of Cardiac Surgery, March 21, 2013
12 Meta-Analysis of Carvedilol Versus Beta 1 Selective Beta-Blockers (Atenolol, Bisoprolol, Metoprolol, and Nebivolol) The American Journal of Cardiology, February 26, 2013 Evidence Based Medicine Review Article
13 Relation of Statin Therapy to Psychological Functioning in Patients With an Implantable Cardioverter Defibrillator The American Journal of Cardiology, April 8, 2013
14 Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study JACC - Journal of the American College of Cardiology, April 12, 2013
15 Improving the use of direct oral anticoagulants in atrial fibrillation European Journal of Internal Medicine , April 12, 2013
16 Ranolazine-Induced Myopathy in a Patient on Chronic Statin Therapy Journal of Clinical Neuromuscular Disease, April 8, 2013
17 Effect of Metoprolol Versus Carvedilol on Outcomes in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) JACC - Journal of the American College of Cardiology, April 3, 2013
18 Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry American Heart Journal, April 1, 2013
19 Enalapril And Carvedilol for Preventing Chemotherapy-Induced Left Ventricular Systolic Dysfunction in Patients with Malignant Hemopathies. The OVERCOME Trial JACC - Journal of the American College of Cardiology, April 12, 2013
20 The Influence of Smoking Status on the Pharmacokinetics and Pharmacodynamics of Clopidogrel and Prasugrel: The PARADOX Study JACC - Journal of the American College of Cardiology, April 25, 2013
Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
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