MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, to pediatrics and General Medical News our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
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25-hydroxyvitamin D levels associated with all-cause and cardiovascular deaths
1 Do patients on statins also need niacin Full Text JAAPA, June 19, 2013 Clinical Article
2 LDL-cholesterol versus non-HDL-to-HDL-cholesterol ratio and risk for coronary heart disease in type 2 diabetes European Journal of Preventive Cardiology, June 19, 2013 Clinical Article
3 Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks Arteriosclerosis, Thrombosis, and Vascular Biology, June 19, 2013 Clinical Article
4 Mechanisms of coronary thrombosis in cigarette smoke exposure Arteriosclerosis, Thrombosis, and Vascular Biology, June 19, 2013 Clinical Article
5 Impaired lipoprotein processing in HIV patients on antiretroviral therapy Arteriosclerosis, Thrombosis, and Vascular Biology, June 19, 2013 Clinical Article
6 Hyperlipidemia attenuates vascular endothelial growth factor–induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells Arteriosclerosis, Thrombosis, and Vascular Biology, June 19, 2013 Clinical Article
7 Socioeconomic status and dyslipidemia in Korean adults: The 2008-2010 Korea National Health and Nutrition Examination Survey Preventive Medicine, June 19, 2013 Clinical Article
8 Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor Circulation, June 19, 2013 Clinical Article
9 Pro-atherogenic lipid changes and decreased hepatic LDL receptor expression by tocilizumab in rheumatoid arthritis Atherosclerosis, June 19, 2013 Clinical Article
10 Lipid profiles for HER2-positive breast cancer Anticancer Research, June 19, 2013 Clinical Article
11 Direct-to-consumer television advertising exposure, diagnosis with high cholesterol, and statin use Journal of General Internal Medicine, June 19, 2013 Evidence Based Medicine Clinical Article
12 Multimodality imaging of carotid atherosclerotic plaque: Going beyond stenosis Full Text Indian Journal of Radiology and Imaging, June 19, 2013
13 Lipoprotein abnormalities in patients with type 2 diabetes and metabolic syndrome Full Text JAAPA, June 19, 2013 Clinical Article
14 Cardiovascular disease: Is LDL-C level a good indicator of coronary risk in people with nondialysis-dependent CKD Nature Reviews Nephrology, June 19, 2013
15 Activation of the mitochondrial ATP-sensitive K+ channel reduces apoptosis of spleen mononuclear cells induced by hyperlipidemia Full Text Lipids in Health and Disease, June 18, 2013
16 Analysis and modelling of cholesterol and high-density lipoprotein cholesterol changes across the range of C-reactive protein levels in clinical practice as an aid to better understanding of inflammation-lipid interactions Annals of Rheumatic Diseases, June 18, 2013 Clinical Article
17 Targeting of Acyl-CoA synthetase 5 decreases jejunal fatty acid activation with no effect on dietary long-chain fatty acid absorption Full Text Lipids in Health and Disease, June 18, 2013
18 CKD and cardiovascular disease in the atherosclerosis risk in communities (ARIC) study: Interactions with age, sex, and race American Journal of Kidney Diseases, June 18, 2013 Clinical Article
19 New therapies to reduce low-density lipoprotein cholesterol Current Opinion in Cardiology, June 17, 2013 Clinical Article
20 Recent clinical trials evaluating benefit of drug therapy for modification of HDL cholesterol Current Opinion in Cardiology, June 17, 2013 Clinical Article
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryAs published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryAs published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summary1 Effects of rosuvastatin versus atorvastatin on small dense low-density lipoprotein: a meta-analysis of randomized trials Heart and Vessels, May 8, 2013 Evidence Based Medicine Review Article
2 Effect of Intensive Versus Moderate Lipid-Lowering Therapy on Epicardial Adipose Tissue in Hyperlipidemic Post-Menopausal Women JACC - Journal of the American College of Cardiology, May 10, 2013
3 Phytosterol capsules and serum cholesterol in hypercholesterolemia: A randomized controlled trial Atherosclerosis, May 14, 2013
4 The Effects of Ezetimibe/Simvastatin versus Simvastatin Monotherapy on Platelet and Inflammatory Biomarkers in Patients with Metabolic Syndrome Cardiology, May 9, 2013
5 Factors underlying regression of coronary atheroma with potent statin therapy European Heart Journal, May 6, 2013
6 Blood Cholesterol Trends 2001-2011 in the United States: Analysis of 105 Million Patient Records PLOS ONE, May 20, 2013 Review Article
7
Use of Lipid-lowering Agents in Rheumatoid Arthritis: A Population-based Cohort Study
The Journal of Rheumatology, May 2, 2013
Exclusive Author Commentary
8 Dietary fatty acids and lipoprotein metabolism: new insights and updates Current Opinion in Lipidology, May 24, 2013 Review Article
9 Analysis of the frequency and spectrum of mutations recognised to cause familial hypercholesterolaemia in routine clinical practice in a UK specialist hospital lipid clinic Atherosclerosis, May 16, 2013
10 LDL cholesterol-lowering effects of grape extract used as a dietary supplement on healthy volunteers International Journal of Food Sciences and Nutrition, May 23, 2013
11 Relation Between Optimism and Lipids in Midlife The American Journal of Cardiology, May 3, 2013
12 Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors BMC Infectious Diseases, May 6, 2013 Free full text
13 Impact of Adding Ezetimibe to Statin to Achieve Low-Density Lipoprotein Cholesterol Goal (from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE] Trial) The American Journal of Cardiology, May 17, 2013
14 Non-HDL-cholesterol/HDL-cholesterol is a better predictor of metabolic syndrome and insulin resistance than apolipoprotein B/apolipoprotein A1 International Journal of Cardiology, April 4, 2013
15 Prognostic value of myocardial circumferential strain for incident heart failure and cardiovascular events in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis European Heart Journal, May 6, 2013
16 The Value of Carotid Artery Plaque and Intima-Media Thickness for Incident Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis Journal of the American Heart Association, May 6, 2013 Free full text
17 The association of elective hormone therapy with changes in lipids among glucose intolerant postmenopausal women in the diabetes prevention program Metabolism, May 9, 2013
18 Statins and lipid metabolism Current Opinion in Lipidology, May 24, 2013 Review Article
19 LDL cholesterol in CKD-to treat or not to treat? Kidney International, May 23, 2013
20 Statins and lipid metabolism Current Opinion in Lipidology, May 30, 2013 Review Article
Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
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