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Cardiology - Basic Science/Genetics News & Articles
MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
Your Unread Messages in Cardiology
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Articles
Latest (1) Full Text Articles (324) Focus on MI441 Multimodal imaging in the diagnosis of isolated left ventricular noncompaction Herz, July 24, 2012
442 Mechanical regulation of cellular phenotype: implications for vascular tissue regeneration Full Text Cardiovascular Research, July 20, 2012
443 Emerging role of G protein-coupled receptors in microvascular myogenic tone Full Text Cardiovascular Research, July 20, 2012
444 Mitochondria in vascular disease Full Text Cardiovascular Research, July 20, 2012
445 Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling Full Text Cardiovascular Research, July 20, 2012
446 Contribution of monocyte-derived macrophages and smooth muscle cells to arterial foam cell formation Full Text Cardiovascular Research, July 20, 2012
447 Smooth muscle cell phenotypic switching in atherosclerosis Full Text Cardiovascular Research, July 20, 2012
448 MicroRNAs and atherosclerosis: New actors for an old movie Nutrition, Metabolism & Cardiovascular Diseases, July 19, 2012
449 Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells Journal of Molecular and Cellular Cardiology, July 18, 2012
450 CXCR4 gene transfer prevents pressure overload induced heart failure Journal of Molecular and Cellular Cardiology, July 18, 2012
451 Sca-1 Knockout Impairs Myocardial and Cardiac Progenitor Cell Function Circulation Research, July 17, 2012
452 PKCβII modulation of myocyte contractile performance Journal of Molecular and Cellular Cardiology, July 17, 2012
453 Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest Journal of Molecular and Cellular Cardiology, July 17, 2012
454 T-type Ca2+ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes Journal of Molecular and Cellular Cardiology, July 17, 2012
455 Disease profile and differential diagnosis of hereditary transthyretin-related amyloidosis with exclusively cardiac phenotype: an Italian perspective European Heart Journal, July 16, 2012
456 Disappearance of left ventricular hypertrabeculation/noncompaction and sudden death in a patient with turner mosaic syndrome The American Journal of Cardiology, July 13, 2012
457 S-nitrosation of β-catenin and p120 catenin: a novel regulatory mechanism in endothelial hyperpermeability Circulation Research, July 12, 2012
458 An lrp1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis Circulation Research, July 12, 2012
459 Brugada syndrome phenotype cardiac arrest in a young patient unmasked during the acute phase of amiodarone infusion: disclosure and aggravation of Brugada electrocardiographic pattern Journal of Electrocardiology, July 11, 2012
460 Torsades de pointes following acute myocardial infarction: Evidence for a deadly link with a common genetic variant Heart Rhythm, July 11, 2012
Clinical Pearls in Cardiology
- Intracoronary abciximab when compared to intravenous abciximab significantly reduces the risk of death among patients with STEMI undergoing PCI
- Thrombolysis in MI (TIMI) scores between 5-14 on admission place patients at high risk for 30-day mortality and should be transferred to a monitored inpatient unit or CCU
- High-sensitivity cardiac troponin T is superior to contemporary sensitive cardiac troponin I in early diagnosis of non-STEMI and the prediction of MI and mortality among patients with suspected ACS
Highlights in Cardiology
Heart failure risk associated with adiponectin level
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryApo B-48 is a marker for CAD
As published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryPost-exercise heart rate recovery predicts cardiac autonomic neuropathy in T2DM
As published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summaryMost Popular Cardiology Articles
Last month's top read Top Articles of 20121 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013
2 Comparison of Double Kissing Crush Versus Culotte Stenting for Unprotected Distal Left Main Bifurcation Lesions : Results From a Multicenter, Randomized, Prospective DKCRUSH-III Study JACC - Journal of the American College of Cardiology, April 2, 2013
3 Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry American Heart Journal, April 1, 2013
4 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article
5 Role of exercise in the prevention of cardiovascular disease: results, mechanisms, and new perspectives European Heart Journal, April 11, 2013
6 Effect of Metoprolol Versus Carvedilol on Outcomes in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) JACC - Journal of the American College of Cardiology, April 3, 2013
7 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
8 Atrial fibrillation-induced cardiac troponin I release International Journal of Cardiology, April 29, 2013
9 L-Carnitine in the Secondary Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis Mayo Clinic Proceedings, April 19, 2013 Evidence Based Medicine Review Article
10 Effect of seven-day atorvastatin pretreatment on the incidence of periprocedural myocardial infarction following percutaneous coronary intervention in patients receiving long-term statin therapy. A randomized study International Journal of Cardiology, April 19, 2013
11 Discovery and Characterization of Alamandine Circulation Research, April 15, 2013
12 Perioperative Dexmedetomidine Improves Outcomes of Cardiac Surgery Circulation, April 24, 2013
13 Effect of Morbid Obesity on In-Hospital Mortality and Coronary Revascularization Outcomes After Acute Myocardial Infarction in the United States The American Journal of Cardiology, April 5, 2013
14 Home-based versus hospital-based high-intensity interval training in cardiac rehabilitation: a randomized study European Journal of Preventive Cardiology, April 25, 2013
15 Long-term clinical follow-up of the multicenter, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES) European Heart Journal, April 11, 2013
16 Left Ventricular Diastolic Dysfunction in Patients With Mitral Stenosis Undergoing Percutaneous Mitral Balloon Valvotomy Mayo Clinic Proceedings, April 9, 2013
17 Reduction of Stent Thrombosis in Patients with Acute Coronary Syndrome Treated with Rivaroxaban in ATLAS ACS 2-TIMI 51 JACC - Journal of the American College of Cardiology, April 26, 2013
18 Outcome of Combined Stenotic and Regurgitant Aortic Valve Disease JACC - Journal of the American College of Cardiology, April 4, 2013
19 Enalapril And Carvedilol for Preventing Chemotherapy-Induced Left Ventricular Systolic Dysfunction in Patients with Malignant Hemopathies. The OVERCOME Trial JACC - Journal of the American College of Cardiology, April 12, 2013
20 Efficacy and safety of dabigatran etexilate and warfarin in real world patients with atrial fibrillation: A prospective nationwide cohort study JACC - Journal of the American College of Cardiology, April 15, 2013
Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
Other Topics in Cardiology
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