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Cardiology - Basic Science/Genetics News & Articles
MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, to pediatrics and General Medical News our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
Your Unread Messages in Cardiology
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25-hydroxyvitamin D levels associated with all-cause and cardiovascular deaths
Articles
Latest Full Text Articles (324) Focus on Arrhythmias381 Role of advanced glycation end products in hypertension and cardiovascular risk: human studies Journal of the American Society of Hypertension, December 17, 2012
382 Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y2 receptor promoter disrupt multiple transcriptional response motifs Journal of Hypertension, December 17, 2012
383 Micro-techniques for analysis of human adipose tissue fatty acid composition in dietary studies Nutrition, Metabolism & Cardiovascular Diseases, December 13, 2012
384 Optical imaging of arrhythmias in the cardiomyocyte monolayer Heart Rhythm, December 5, 2012
385 17(beta)-Estradiol enhances the recruitment of bone marrow-derived endothelial progenitor cells into infarcted myocardium by inducing CXCR4 expression International Journal of Cardiology, December 4, 2012
386 Time-dependent Cox regression: Serial measurement of the cardiovascular biomarker proadrenomedullin improves survival prediction in patients with lower respiratory tract infection International Journal of Cardiology, December 4, 2012
387 Recent progress in elucidating signalling proteolytic pathways in muscle wasting: Potential clinical implications Nutrition, Metabolism & Cardiovascular Diseases, November 27, 2012
388 The Notch pathway controls fibrotic and regenerative repair in the adult heart European Heart Journal, November 20, 2012
389 Common Polymorphisms in the CYP11B1 and CYP11B2 Genes: Evidence for a Digenic Influence on Hypertension Hypertension, November 15, 2012
390 Effect of CYP3A5, CYP3A4, and ABCB1 Genotypes as Determinants of Tacrolimus Dose and Clinical Outcomes After Heart Transplantation Transplantation Proceedings, November 15, 2012
391 Functional Regulation of ClC-3 in the Migration of Vascular Smooth Muscle Cells Hypertension, November 15, 2012
392 Circulating microRNAs as diagnostic biomarkers for cardiovascular diseases American Journal of Physiology - Heart and Circulatory Physiology, November 14, 2012
393 Quantitative expression of the mutated lamin a/c gene in patients with cardiolaminopathy JACC - Journal of the American College of Cardiology, November 14, 2012
394 Smooth muscle cell plasticity: fact or fiction? Circulation Research, November 13, 2012
395 Association of CYP2C19*2 and *3 Genetic Variants with Essential Hypertension in Koreans Full Text Yonsei Medical Journal, November 9, 2012
396 Pressure Overload Regulates Expression of Cytokines, γH2AX, and Growth Arrest- and DNA-Damage Inducible Protein 153 via Glycogen Synthase Kinase-3 β in Ischemic-Reperfused Hearts Hypertension, November 8, 2012
397 Interleukin-6 receptor pathways in abdominal aortic aneurysm European Heart Journal, November 2, 2012
398 Effects of Intracoronary Cd34+ Stem Cell Transplantation in Non-Ischemic Dilated Cardiomyopathy Patients: 5-Year Follow Up Circulation Research, November 2, 2012
399 hERG Activation Gating Is Rapid: Evidence from Gating-Current Recordings and MTSET Modification of the Voltage Sensor Heart Rhythm, October 31, 2012
400 Optogenetics: Controlling Cardiac Depolarization and Hyperpolarization Using Combined Cell and Gene Therapy and Light-Sensitive Proteins Heart Rhythm, October 29, 2012
Clinical Pearls in Cardiology
- Intracoronary abciximab when compared to intravenous abciximab significantly reduces the risk of death among patients with STEMI undergoing PCI
- Thrombolysis in MI (TIMI) scores between 5-14 on admission place patients at high risk for 30-day mortality and should be transferred to a monitored inpatient unit or CCU
- High-sensitivity cardiac troponin T is superior to contemporary sensitive cardiac troponin I in early diagnosis of non-STEMI and the prediction of MI and mortality among patients with suspected ACS
Highlights in Cardiology
Heart failure risk associated with adiponectin level
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryApo B-48 is a marker for CAD
As published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryPost-exercise heart rate recovery predicts cardiac autonomic neuropathy in T2DM
As published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summaryMost Popular Cardiology Articles
Last month's top read Top Articles of 2012Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
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