The Latest Journal Articles in Cardiology

1Effects of oral treatments on clinical outcomes in pulmonary arterial hypertension: a systematic review and meta-analysisAmerican Heart Journal, April 21, 2015  Clinical Article  Evidence Based Medicine  Review Article
2Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trialThe Lancet, April 21, 2015  Clinical Article  Evidence Based Medicine
3Medical nutrition therapy is the essential cornerstone for effective treatment of refractory severe hypertriglyceridemia regardless of pharmaceutical treatment: Evidence from a Lipid Management ProgramJournal of Clinical Lipidology, April 21, 2015  Clinical Article
4Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in strokeNew England Journal of Medicine, April 21, 2015  Clinical Article  Evidence Based Medicine
5Statin recapture therapy before coronary artery bypass grafting (StaRT-CABG Trial): rationale and study design of a multicenter, randomized, double-blinded controlled clinical trialAmerican Heart Journal, April 21, 2015  Clinical Article
6Fenofibrate lowers atypical sphingolipids in plasma of dyslipidemic patients – a novel approach for treating diabetic neuropathyJournal of Clinical Lipidology, April 21, 2015  Clinical Article
7Cognitive function in survivors of out-of-hospital cardiac arrest after target temperature management at 33°C versus 36°CCirculation, April 21, 2015  Clinical Article
8Effect of central venous angioplasty on hemodialysis access circuit flow: prospective study of 25 symptomatic patientsJournal of Vascular and Interventional Radiology, April 21, 2015  Clinical Article
9Thrombectomy within 8 hours after symptom onset in ischemic strokeNew England Journal of Medicine, April 21, 2015  Clinical Article  Evidence Based Medicine
10Predictors of clinical outcomes in acute decompensated heart failure: ASCEND-HF outcome modelsAmerican Heart Journal, April 21, 2015  Clinical Article
1VU team's cattle research may yield lung disease cluesVanderbilt University Medical Center Research News, April 21, 2015
2Cardiorespiratory fitness reduces disease risk among smokersUniversity of Texas Health Science Center at Houston News, April 21, 2015
3Eating out = high blood pressure?Duke-NUS Graduate Medical School Singapore News, April 21, 2015
4Systems-wide genetic investigation of blood pressure regulation in the Framingham Heart StudyEMBO News, April 21, 2015
5Shorter height is directly associated with increased risk of coronary heart diseaseUniversity of Leicester News, April 20, 2015
6Some atrial fibrillation patients receive unnecessary blood thinnersUCSF News, April 20, 2015
7Sharp uptick in youth e-cigarette use an alarming trend, says American Heart AssociationAmerican Heart Association News, April 20, 2015
8Survey shows half of older adults in U.S. now taking aspirinOregon State University News, April 20, 2015
9Genetics overlap found between Alzheimer's disease and cardiovascular risk factorsUC San Diego Health System, April 20, 2015
10NIH launches largest clinical trial focused on HIV-related cardiovascular diseaseNIH News, April 17, 2015

Show Me:

Fructosamine and glycated albumin predict incident diabetes

As reported in The Lancet, fructosamine and glycated albumin > 95th percentile predicted incident diabetes (HR=4.96 and 6.17, respectively) and retinopathy and chronic kidney disease among 958 and 11348 patients with and without diabetes, respectively, followed for 20 years.

Vitamin D supplementation improves ejection fraction

As reported in Nutrition, Metabolism, and Cardiovascular Diseases, vitamin D supplementation (4000 IU/d of cholecalciferol x 6 months) of vitamin D-deficient heart failure patients (n=23) resulted in an increase in the ejection fraction compared to placebo (6.7 vs. -4.3%).

Muscle strength in adolescence decreases CVD risk

As reported in BMC Medicine, adolescents (n=38588) with the highest tertile of muscle strength had a decreased risk of CVD (HR=0.88) compared to adolescents with the lowest tertile of muscle strength after 42 y of follow-up. Of note, low muscle strength in adolescence by itself had no effect on CVD risk in middle age (HR=0.99). In contrast, high muscle strength in adolescence significantly decreased the risk of CVD in middle age (HR=1.31).

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Clinical Pearl from Smartest DocApixaban, dabigatran and rivaroxaban are cost-effective alternatives to warfarin for stroke prevention in AF.

Clinical Pearl from Smartest DocThe DASH diet reduces high-sensitivity C-reactive protein levels in adolescents with metabolic syndrome.

Clinical Pearl from Smartest DocThe workup for asymptomatic murmurs in children does not require an echocardiogram.

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