Fructosamine and glycated albumin predict incident diabetes
As reported in The Lancet, fructosamine and glycated albumin > 95th percentile predicted incident diabetes (HR=4.96 and 6.17, respectively) and retinopathy and chronic kidney disease among 958 and 11348 patients with and without diabetes, respectively, followed for 20 years.
AGEs increase cardiovascular risk in T2DM
As reported in Diabetes, elevated advanced glycation end products increase the risk for incident cardiovascular events (HR=1.31) in type 2 diabetics (n=218).
Rho-associated kinase activity is a biomarker for cardiovascular events
As reported in Hypertension, rho-associated kinase activity is an independent predictor of cardiovascular events. The study involved 633 patients undergoing routine health screening examinations with a median follow-up of 42 months. There were 29 cardiovascular-related deaths, 2 myocardial infarctions, 20 revascularizations, 15 strokes, and 17 hospitalizations for heart failure. The HRs for first cardiovascular event, death, stroke, and revascularization were 2.19, 2.57, 2.14, and 2.68, respectively.