LMI1195 PET imaging in evaluation of regional cardiac sympathetic denervation and its potential role in antiarrhythmic drug treatment
European Journal of Nuclear Medicine & Molecular Imaging, 08/17/2012
Yu M et al. – LMI1195 exhibits high association with noradrenaline transporter and can be used for imaging Regional cardiac sympathetic denervation (RCSD). The detected RCSD increases cardiac risks to the antiarrhythmic drug, dofetilide, by inducing more QTc prolongation.