Adipokines, Ghrelin and Obesity-Associated Insulin Resistance in Nondiabetic Patients with Acute Coronary Syndrome
Barazzoni R et al. – In acute coronary syndromes (ACS) patients, obesity and obesity–related changes in plasma leptin and adiponectin are associated with and likely contribute to negatively modulate insulin resistance. ACS per se does not however enhance the negative impact of obesity on insulin sensitivity. High acylated and low desacylated ghrelin characterize ACS patients independently of obesity, but are not associated with insulin sensitivity.