mdlinx mdlinx
Latest (66) Full Text Articles (3243) Focus on Hypertension Article Summary

The Uncoupling Protein 2 -866G > A Polymorphism is Associated with the Risk of Ischemic Stroke in Chinese Type 2 Diabetic Patients
CNS Neuroscience & Therapeutics,  Clinical Article

Chai Y et al. – The A allele of the –866G>A variant of UCP2 was associated with increased risk of IS in Chinese diabetic women with type 2 diabetes in a 4–year prospective study. This association was independent of other common IS risk factors.

Methods
  • A total of 844 type 2 diabetic patients with 4-year prospective study were examined using a case-control methodology.
  • And 404 cases with ischemical stroke, 440 cases without ischemical stroke.
  • The -866G>A polymorphism in UCP2 was genotyped by TaqMan MGB probe method.

Results
  • The -866G>A SNP in UCP2 was significantly associated with diabetic ischemical stroke (odds ratio [OR]=1.94; 95% confidence interval [CI]= 0.68 to1.31; P < 0.037).
  • Similar results were observed for baseline cases of IS.
  • Stratification by sex confirmed an allelic association with IS in women, whereas no association was observed in men.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

    Currently, there are no available articles.

Your Unread Messages in Cardiology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Cardiology Articles

Last month's top read Top Articles of 2013

Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heartmore

Other Topics in Cardiology

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Stay current - Media Tool

Newsletter
RSS
Follow
Like

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close