Intraoperative Changes in Regional Wall Motion: Can Postoperative Coronary Artery Bypass Graft Failure Be Predicted
Journal of Cardiothoracic and Vascular Anesthesia, 04/10/2012
De Mey N et al. – In this retrospective study, regional wall motions abnormalities (RWMAs) detected with transesophageal echocardiography (TEE) were of limited value to predict early postoperative coronary artery bypass graft (CABG) failure.
Five thousand nine hundred ninety-eight patients who underwent coronary artery bypass graft (CABG) surgery.
An evaluation of RWMAs recorded with intraoperative TEE before and after cardiopulmonary bypass (CPB) in patients who had coronary angiography for suspected postoperative myocardial ischemia based on electrocardiogram (ECG), CK-MB, troponin T, hemodynamic compromise, low cardiac output, and malignant ventricular arrhythmia.
Sensitivity, specificity, positive and negative predictive values, odds ratio, 95% confidence interval, and chi-square analysis were used.
Thirty-nine patients (0.7%) underwent early coronary angiography for the suspicion of early graft dysfunction.
Of the 32 patients with diagnosed early graft dysfunction, 5 patients (15.6%) had shown new intraoperative RWMAs as detected by TEE, 21 patients (65.6%) had no new RWMAs, no report was available in 5 patients (15.6%), and 1 examination (3.1%) was excluded because of poor imaging quality.
The sensitivity of TEE to predict graft failure was 15.6%, the specificity was 57.1%, and the positive predictive and negative values were 62.5% and 12.9%, respectively.
The odds ratio and 95% confidence interval was 0.1190 (0.0099-1.4257) when TEE was positive compared with coronary angiography.
No association was found between new RWMAs detected with TEE and graft failure as documented with coronary angiography (p=0.106).
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