Journal of Clinical Lipidology, 10/11/2011Cibickova L et al.
Better understanding of the effects of statins on brain metabolism becomes more important because many studies bring evidence of a possible link between cholesterol and neurodegeneration.
The MEDLINE database.
According to the data reported thus far, statins may influence brain cholesterol metabolism directly (because they are able to penetrate BBB no matter whether they are hydrophilic or lipophilic) and also indirectly (by lowering plasma cholesterol).
Although the definite mechanism is not known yet, it becomes obvious that statins do not only influence peripheral but also central cholesterol pool.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.