Future directions in vitamin D and cardiovascular research
Nutrition, Metabolism & Cardiovascular Diseases, 05/30/2012Zittermann A et al.
Overall, it can be expected that the next 10–15 years will provide an increased clarity concerning the role of vitamin D in CVD.
Future directions include the need of performing large randomised controlled supplementation trials with vitamin D in specific risk groups.
In addition, large register sets of data on vitamin D supplementation can be used, provided that adequate statistical methods such as propensity score modelled analysis are applied.
To better understand vitamin D–mediated effects on CVD risk, the routine measurement of circulating levels of the hormonal vitamin D form, 1,25–dihydroxyvitamin D, is also necessary, in addition to the determination of its precursor 25–hydroxyvitamin D.
Further, genetic association studies may help in clarifying the contribution of vitamin D to the development of CVD.
Finally, the interrelationship of vitamin D with physical activity should be considered when studying CVD risk.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.