Human group X secreted phospholipase A2 induces dendritic cell maturation through lipoprotein-dependent and -independent mechanisms

Atherosclerosis, 05/25/2012

hGX–sPLA2 secreted in inflamed tissues can contribute to local DC maturation, resulting in pro–Th1 cells, through the production of various lipid mediators from hydrolysis of either LDL and/or cell plasma membrane.

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