The prevalence of early repolarization in patients with noncompaction cardiomyopathy presenting with malignant ventricular arrhythmias
Journal of Cardiovascular Electrophysiology, 05/16/2012
There is a high prevalence of ER in noncompaction cardiomyopathy (NCCM) patients, especially in those who present with malignant ventricular arrhythmias.
Authors analyzed prospective data from this NCCM registry including 84 patients, median age: 40 (3–79) years.
Fourteen patients (17%) initially presented with sustained VT (n = 5) or VF (n = 9) and 70 (83%) with heart failure or else.
After the exclusion of 20 patients with the left bundle branch block, 25 (39%) NCCM patients had ER; 3 (6%) located in inferior leads, 14 (27%) in lateral leads, and 8 (15%) in both.
None had ER in leads V1 to V3.
In those presenting with VT/VF, 9/12 (75%) had ER (2 in inferior leads, 3 in lateral leads and 4 in both), versus 16/52 (31%) in the other patients (P = 0.02).
If the NCCM population was dichotomized according to the presence or absence of ER, the long–term outcome for VT/VF appeared worse in the ER positive patients (P = 0.05).