Transmurality of scar influences the effect of a hybrid-intervention with autologous bone marrow cell injection and aortocoronary bypass surgery (MNC/CABG) in patients after myocardial infarction

International Journal of Cardiology, 05/08/2012

A single hybrid intervention of MNC recovery, purification and injection with CABG–surgery (MNC/CABG) may be an attractive modality for cell therapy. However, no regeneration of avital transmural scar tissue seems to occur, while the contribution of MNC to improved perfusion in non–transmural myocardial infarct scars remains to be determined.

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