Association of a functional single-nucleotide polymorphism in the ALDH2 gene with essential hypertension depends on drinking behavior in a Chinese Han population

Journal of Human Hypertension, 05/04/2012

Authors present evidence for the association of rs671 in the ALDH2 gene with susceptibility to essential hypertension (EH), increase in blood pressure (BP) and disturbance of serum lipid profiles in drinkers, but not in nondrinkers. Further functional research is warranted to elucidate the role of rs671 in the variation of BP and lipid levels in EH.

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