Drug-Eluting vs Bare-Metal Stents in Primary Angioplasty

JAMA Internal Medicine, 04/26/2012

The present pooled patient–level meta–analysis demonstrates that among patients with ST–segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, sirolimus–eluting and paclitaxel–eluting stents compared with bare–metal stents are associated with a significant reduction in target–vessel revascularization at long–term follow–up. Although there were no differences in cumulative mortality, reinfarction, or stent thrombosis, the incidence of very late reinfarction and stent thrombosis was increased with these Drug–Eluting stent.

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