Factors predicting early- and long-term survival in patients undergoing extracorporeal membrane oxygenation (ecmo)

Journal of Cardiac Surgery, 03/16/2012

Early extracorporeal membrane oxygenation (ECMO) application before catastrophic clinical deterioration and weaning as soon as possible may enhance overall survival.

Methods

  • Authors reviewed the records of 185 patients who received ECMO support for various medical conditions between January 2005 and January 2010.
  • Risk factors for successful weaning, early mortality, and overall survival were investigated.

Results

  • There were 101 males and 84 females, and the mean age was 56.1 ± 14.7 years.
  • Patients received either venoarterial (n = 137) or veno–veno (n = 48) ECMO.
  • ECMO was instituted in stable patients (n = 40, 21.6%), those in shock (n = 105, 56.8%), or those in cardiac arrest (n = 40, 21.6%).
  • Mean ECMO support lasted 4.7 days and weaning was successful in 68 patients (36.7%), with 38 (20.5%) eventually being discharged from the hospital.
  • Univariate analysis showed hemodynamic status at insertion (p = 0.05) including intra–aortic balloon pump usage to significantly influence successful weaning, whereas the duration of ECMO was strongly associated with overall survival (p = 0.05).

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