MDLinx Cardiology – on this page: Articles from over 2,000 of the peer-reviewed medical journals, pre-sorted and ranked by what’s most relevant to your day-to-day practice, and summarized to save you precious time. From vascular disorders and stroke to valvular disorders, coronary artery disease and arrhythmias, our physician editors make sure that all members of your heart health team can be current on the literature in 5 minutes or less every day.
Also on this page: Bonus content exclusive to MDLinx, clinical pearls from The Smartest Cardiologist daily quiz competition and Cardiology Physician Review. Plus, the “must-read” articles related to cardiology, personally chosen by our physician editor, D. Scott Cunningham, MD, PhD.
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1 Operative mortality and stroke after on-pump vs off-pump surgery in high-risk patients: an analysis of 83 914 coronary bypass operations European Journal of Cardio-Thoracic Surgery, May 20, 2013 Clinical Article
2 Triple Therapy With Aspirin, Prasugrel, and Vitamin K Antagonists in Patients With Drug-Eluting Stent Implantation and an Indication for Oral Anticoagulation JACC - Journal of the American College of Cardiology, May 20, 2013 Clinical Article
3 Long-Term Survival of Patients Undergoing Mitral Valve Repair and Replacement Circulation, May 20, 2013 Clinical Article
4 Risk of hypertension in cancer patients treated with sorafenib: an updated systematic review and meta-analysis Journal of Human Hypertension, May 20, 2013 Evidence Based Medicine Review Article Clinical Article
5 A systematic review and meta-analysis of genotype-phenotype associations in patients with hypertrophic cardiomyopathy caused by sarcomeric protein mutations Heart, May 20, 2013 Review Article
6 Esomeprazole and aspirin fixed combination for the prevention of cardiovascular events Full Text Vascular Health and Risk Management, May 20, 2013 Clinical Article
7 Blood Cholesterol Trends 2001-2011 in the United States: Analysis of 105 Million Patient Records PLOS ONE, May 20, 2013 Review Article
8 Multidetector Computed Tomography for Coronary Stents Imaging: High-Voltage (140-kVp) Prospective ECG-Triggered Versus Standard-Voltage (120-kVp) Retrospective ECG-Gated Helical Scanning Journal of Computer Assisted Tomography, May 20, 2013 Clinical Article
9 Surgical Management of Apical Muscular Ventricular Septal Defects Using the Sandwich Technique Journal of Cardiac Surgery, May 20, 2013 Clinical Article
10 C-Reactive Protein, Lipid-soluble Micronutrients, and Survival in Colorectal Cancer Patients Cancer Epidemiology, Biomarkers & Prevention, May 20, 2013 Clinical Article
11 Orthostatic Hypotension and the Risk of Congestive Heart Failure: A Meta-Analysis of Prospective Cohort Studies PLOS ONE, May 20, 2013 Evidence Based Medicine
12 Atrial fibrillation - inflammation in disguise? Scandinavian Journal of Immunology, May 20, 2013 Review Article
13 In Vivo Evaluation of Carotid Artery Stents Using Multi-Detector-Row Computed Tomography Angiography: Comparison of 3 Kernels Journal of Computer Assisted Tomography, May 20, 2013 Clinical Article
14 Impact of normalization strategy on cardiac expression of pro-inflammatory cytokines: Evaluation of reference genes in different human myocardial regions after Left Ventricular Assist Device support Cytokine, May 20, 2013 Clinical Article
15 Concomitant Replacement of the Dilated Ascending Aorta During Aortic Valve Replacement; Does It Increase the Perioperative Morbidity and Mortality Risks Journal of Cardiac Surgery, May 20, 2013 Clinical Article
16 Surgical Repair of Coronary Artery Fistula Combined with Coronary Artery Ectasia in Adults Journal of Cardiac Surgery, May 20, 2013 Clinical Article
17 Transcatheter Aortic Valve Insertion Catastrophe in Inoperable Patients: Should Aortic Valve Replacement Be Denied Journal of Cardiac Surgery, May 20, 2013 Clinical Article
18 Insertion of an Abiomed Impella Left Ventricular Assist Device Following Bioprosthetic Aortic Valve Placement Journal of Cardiac Surgery, May 20, 2013 Clinical Article
19 The effect of aerobic exercise intensity on attenuation of postprandial lipemia is dependent on apolipoprotein E genotype Atherosclerosis, May 20, 2013 Clinical Article
20 Innominate Artery as an Alternative Site for Proximal Anastomoses in Patients With a Severely Calcified Aorta Journal of Cardiac Surgery, May 20, 2013 Clinical Article
As published in Obesity, a J-shaped association between adiponectin level and heart failure exists. The study involved 787 males with heart failure and 787 healthy controls from the Physicians’ Health Study. The relative risk of heart failure from lowest to highest quintile of adiponectin level was 0.74, 0.67, 0.70, and 0.92.
Read the article summaryAs published in the European Journal of Clinical Investigation, fasting serum apo B-48 levels were elevated in patients with Coronary Artery Disease (n=96; 6.9 µg/mL) compared to patients without CAD (n=67; 3.9 µg/mL). Along with other cardiac risk factors, an apo B-48 level > 4.34 µg/mL was predictive of CAD.
Read the article summaryAs published in Diabetic Medicine, cardiac autonomic neuropathy can be predicted in patients with T2DM and negative exercise echocardiograms based on post-exercise heart rate recovery. Of the 135 study subjects, 27 (20%) had cardiac autonomic neuropathy, the criteria for which included > 2 of 7 autonomic function markers (4 cardiac reflex tests and 3 indices of short-term heart rate variability). The optimal cut-offs for post-exercise heart rate recovery at 1-, 2-, and 3-minutes were < 28, < 50, and < 52 beats per minute, respectively.
Read the article summary1 Effect of Metoprolol Versus Carvedilol on Outcomes in MADIT-CRT (Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy) JACC - Journal of the American College of Cardiology, April 3, 2013
2 Rate versus rhythm control for management of atrial fibrillation in clinical practice: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry American Heart Journal, April 1, 2013
3 The long QT syndrome: a transatlantic clinical approach to diagnosis and therapy European Heart Journal, April 9, 2013 Review Article
4 Effect of coenzyme q10 supplementation on statin-induced myalgias The American Journal of Cardiology, July 30, 2012
5 Chlorthalidone Versus Hydrochlorothiazide for the Treatment of Hypertension in Older Adults A Population-Based Cohort Study Annals of Internal Medicine, March 19, 2013
6 Statins and autoimmunity Immunologic Research, April 17, 2013 Review Article
7 Meta-Analysis of Carvedilol Versus Beta 1 Selective Beta-Blockers (Atenolol, Bisoprolol, Metoprolol, and Nebivolol) The American Journal of Cardiology, February 26, 2013 Evidence Based Medicine Review Article
8 Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial The Lancet, April 18, 2013
9 Clinical Update on the Management of Atrial Fibrillation Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, April 10, 2013
10 Treatment of Hypertension Among African Americans: The Jackson Heart Study The Journal of Clinical Hypertension, April 5, 2013
11 Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial European Heart Journal, April 22, 2013
12 Pulmonary hypertension: diagnosis and management British Medical Journal, April 23, 2013 Review Article
13 Effect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomised trials British Medical Journal, April 25, 2013 Evidence Based Medicine Review Article
14 Infective Endocarditis New England Journal of Medicine, April 24, 2013 Review Article
15 Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient International Journal of General Medicine, April 2, 2013 Free full text
16 Comparison of Prasugrel and Ticagrelor Loading Doses in ST-Segment Elevation Myocardial Infarction Patients RAPID (Rapid Activity of Platelet Inhibitor Drugs) Primary PCI Study JACC - Journal of the American College of Cardiology, April 12, 2013
17 Combination therapy in the management of pulmonary arterial hypertension International Journal of Clinical Practice, April 15, 2013 Review Article
18 A double-blind, double-dummy, randomized, placebo-controlled trial to evaluate the effect of statin therapy on triglyceride levels in Mexican hypertriglyceridemic patients Current Medical Research and Opinion, April 16, 2013
19 Long-term clinical follow-up of the multicenter, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES) European Heart Journal, April 11, 2013
20 Can Vitamin D Supplementation Improve the Severity of Congestive Heart Failure? Congestive Heart Failure, April 2, 2013 Free full text
Indexed Journals in Cardiology: American Heart Journal, American Journal of Cardiology, Circulationn, Heart more
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